Search Result

Search Results for " c11 "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T40419	IRES-C11	IRES-C11	c-Myc
	IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans...		c-Myc
T38161	STING Agonist C11	STING Agonist C11
	STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphory...
T39652	BODIPY 581/591 C11	BODIPY 581/591 C11
	C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation . C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 i...
T13773	Mito-apocynin (C11)		Others
	Mito-apocynin (C11) is a mitochondria-targeting antioxidant that works by targeting and neutralizing reactive oxygen species (ROS) produced during cellular respiration. Triphenylphosphonium bromide has been found to be e...		Others
T77971	Pomalidomide-C11-NH2 hydrochloride
	Pomalidomide-C11-NH2 hydrochloride is a cereblon (CRBN) ligand derived from Pomalidomide used to recruit the CRBN protein. This compound can be conjugated with a linker to the protein ligand to assemble a PROTAC [1].
T77981	Pomalidomide-5-C11-NH2 hydrochloride
	Pomalidomide-5-C11-NH2 hydrochloride is a Pomalidomide-derived cereblon (CRBN) ligand that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a protein ligand via a linker to create a PRO...
T77962	Thalidomide-4-O-C11-NH2 hydrochloride
	Thalidomide-4-O-C11-NH2 hydrochloride is a thalidomide-based cereblon ligand for CRBN protein recruitment. It can be conjugated to a protein ligand via a linker to create PROTACs [1].
T77958	Thalidomide-5-O-C11-NH2 hydrochloride
	Thalidomide-5-O-C11-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated to a protein ligand via a linker to synthesize PROTACs [1].
T10640	C-11		Others
	C-11 is a tubulin inhibitor and acts as an ADC cytotoxin with cytotoxicity for carcinoma cell lines.		Others
T32696	Levetimide C-11
	Levetimide C-11 is a radiotracer.
T32289	Jhu-75528c-11	JHU75528 C-11,11c-Omar,JHU 75528 C-11
	JHU-75528 C-11 can be used as a Radiotracer for PET Imaging of CB1 Cannabinoid Receptors.
T23601	ABC1183	ABC 1183,ABC-1183	GSK-3 , CDK
	ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen ...		GSK-3 , CDK
T9083	TC11	CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11	BCL , Caspase , CDK
	TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.		BCL , Caspase , CDK
T12260	NSC117079		Others
	NSC117079 is an inhibitor of PHLPP.		Others
TP2375	C112 Peptide	Ile-arg-pro-val-gln
	C112 Peptide is a novel peptide.
T61177	NSC114126
	NSC114126 is a highly effective and orally bioavailable inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR-TK). This compound exhibits robust antiproliferative properties, making it a...
T70821	FC11409B
	FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.
T73591	C11237
	C11237 is a useful organic compound for research related to life sciences. The catalog number is T73591 and the CAS number is 1806-98-0.
T29261	(S)-Desmethyl-NNC112	(+)-Desmethyl-NNC112
	(S)-Desmethyl-NNC112 is a PET precursor for NNC112.
T84314	BFC1108

T24549	NSC114792	NSC-114792,NSC 114792
	NSC114792 is a selective JAK3 inhibitor.
T69853	AR-C117977
	AR-C117977 is a potent MCT1 inhibitor, which can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance.
T41061	Histone H3 (116-136), C116-136	Histone H3 (116-136), C116-136
	Histone H3 (116-136), C116-136 is a peptide consisting of amino acids 116 to 136, which spans the C-terminus of histone H3.
T77815	EC1167 hydrochloride
	EC1167 hydrochloride serves as the linker for EC1169, a prostate-specific membrane antigen-targeting tubulysin conjugate. EC1169 hydrochloride demonstrates potential in treating recurrent metastatic, castration-resistant...
T24434	MCC1189	MCC 1189,MCC-1189
	MCC1189 is a first-in-class MFS efflux pump CaMdr1p inhibitor.
T74400	TC113
	TC113, a Gemcitabine (GEM)-based conjugate incorporating the c(RGDyK) sequence, is internalized by A549 cells via the integrin αvβ3 pathway. It demonstrates significant antiproliferative effects on both WM266.4 and A549 ...
TP2374	C111 Peptide	Gly-val-tyr-pro-his-lys
	C111 Peptide is a peptide.
T78179	NH2-UAMC1110 TFA
	NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating agent crucial for creating radiotracers with high tumor selecti...
T17930	EC1167		Others
	EC1169 is a targeted tubulysin conjugate that utilizes EC1167 as its linker. This compound shows promise in the treatment of recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].		Others
T25855	NC1153	CN-1153,NC-1153,NC 1153,CN 1153,CN1153
	NC1153 is a blocker of IL-2-induced activation of JAK3 and its downstream substrates STAT5a/b. It promotes long-term allograft survival and sparing the recipient from multiple toxicities.
T62835	Antitumor agent-54
	Antitumor agent-54 (Compound C11) is a 14-3-3η protein inhibitor (KD: 35 μM). antitumor agent-54 inhibits several typical human hepatocellular carcinoma cell lines. antitumor agent-54 blocks the cell cycle in the G1-S ph...
T37879	N-undecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm forma...
T36384	DL-Tyrosine-13C9,15N	L-Tyrosine-13C9,15N
	L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylal...

Compounds

Synonym: STING Agonist C11

Target:

BODIPY 581/591 C11

T39652

Synonym: BODIPY 581/591 C11

Target:

Mito-apocynin (C11)

T13773

Synonym:

Target: Others

Pomalidomide-C11-NH2 hydrochloride

T77971

Synonym:

Target:

Pomalidomide-5-C11-NH2 hydrochloride

T77981

Synonym:

Target:

Thalidomide-4-O-C11-NH2 hydrochloride

T77962

Synonym:

Target:

Thalidomide-5-O-C11-NH2 hydrochloride

Synonym: JHU75528 C-11,11c-Omar,JHU 75528 C-11

Target:

ABC1183

T23601

Synonym: ABC 1183,ABC-1183

Target: GSK-3, CDK

TC11

T9083

Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

Target: BCL, Caspase, CDK

Synonym: Ile-arg-pro-val-gln

Synonym: (+)-Desmethyl-NNC112

Synonym: NSC-114792,NSC 114792

Histone H3 (116-136), C116-136

T41061

Synonym: Histone H3 (116-136), C116-136

Synonym: MCC 1189,MCC-1189

Synonym: Gly-val-tyr-pro-his-lys

Synonym: CN-1153,NC-1153,NC 1153,CN 1153,CN1153

N-undecanoyl-L-Homoserine lactone

Synonym: L-Tyrosine-13C9,15N

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00481	AKR1C4 Protein, Human, Recombinant (His)	Human	E. coli
	Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ...
TMPH-01472	HDAC11 Protein, Human, Recombinant (GST)	Human	E. coli
	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcrip...
TMPY-03997	COLEC11 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	COLEC11 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 27.70 kDa and the accession number is Q3SXB8-1.
TMPH-03747	CCDC112 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	CCDC112 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.0 kDa and the accession number is Q8NEF3.
TMPH-00108	UBC11 Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	E. coli
	Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC11 Protein, Arabidopsis thaliana, Recombinant...
TMPH-01806	OBP2A Protein, Human, Recombinant (C114S & K127N, His & SUMO)	Human	E. coli
	Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids. OBP2A Protein, Human, Recombinant (C114S & K127N, His & SUMO) is expressed in E. coli express...
TMPH-02110	SEC11C Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
TMPH-01410	GPR84 Protein, Human, Recombinant (hFc)	Human	P. pastoris (Yeast)
	Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and ...