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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6427 | Butein | 2’,3,4,4’-tetrahydroxy Chalcone | Apoptosis , EGFR , Others , PDE , Autophagy |
Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR. | |||
TN7079 | Coreopsin | Butein-4-O-β-D-glucopyranoside | Others |
Coreopsin(Butein-4-O-β-D-glucopyranoside) is one of the main components from Coreopsis tinctoria Nutt. Flower(CTF). CTF has been used traditionally in China for treating hypertension and diabetes as well as reducing body... | |||
TN4220 | Homobutein | 3-O-Methylbutein,2',4,4'-Trihydroxy-3-methoxychalcone | Antioxidant , NF-κB , HDAC , Parasite , Immunology/Inflammation related |
Homobutein (3-O-Methylbutein) is a dual inhibitor of HDACs and NF-κB with IC50s of 190 and 38 μM. Homobutein is an iron chelator with anticancer, anti-inflammatory, antiparasite, and antioxidation activities. | |||
TN3057 | 4-O-Methylbutein | Autophagy | |
4-O-Methylbutein (2',3,4'-trihydroxy-4-methoxychalcone) may have anti-inflammation activity, it is a potent heme oxygenase-1 (HO-1) inducer, the upregulation of HO-1 has proven to be a useful tool for fighting inflammati... |