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Search Results for " bel-7402 "

18

Compounds

Cat No. Product Name Synonyms Targets
T5858 Sertindole Lu 23-174 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
T3S2325 Ardisiacrispin A Saxifragifolin B,LTS-4,Deglucocyclamin HSV
Ardisiacrispin A (Deglucocyclamin) has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and disassembling microtubule...
TN2590 11alpha,12alpha-Oxidotaraxerol palmitate Others
11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780.
T63787 Anticancer agent 62
Anticancer agent 62 is an effective anticancer agent. anticancer agent 62 exhibited anti-proliferative effects on HepG2, Bel-7402 and MCF-7 cancer cells with IC50 values of 0.019, 0.060 and 0.016 μM, respectively. antica...
T64002 Anticancer agent 61
Anticancer agent 61 is an orally active anticancer agent. anticancer agent 61 was able to inhibit the proliferation of HepG2, Bel-7402 and MCF-7 cancer cells with IC50 values of 1.12, 1.97 and 1.08 μM respectively. antic...
T63653 AKT-IN-11
AKT-IN-11 is one of the most potent antibacterial agents against human hepatocellular carcinoma Bel-7402 cell line (IC50: 1.15 μM).
TN4496 Marginatoxin Caspase , Fas/FasL
Marginatoxin may be a promising chemopreventive agent for treating hepatocellular carcinoma, it induces human hepatoma BEL-7402 cells apoptosis in vitro and in vivo via activation of Fas/FasL-mediated apoptotic pathway.
T41133 Ursonic acid methyl ester
Ursonic acid methyl ester, an esterified derivative of Ursolic acid, exhibits growth inhibitory activity against four tumor cell lines: HL-60, BGC, Bel-7402, and Hela, and the ED50 values for inhibition are >100 μg/ml.
TN2184 Schisanlactone E Others
Schisanlactone E may show moderate cytotoxic activity against the human tumor cell lines Bel-7402, BGC-823, MCF-7 and HL-60.
TN3429 Aphagranin A Others
Aphagranin A exhibits strong antiproliferative activity against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823.
T79541 HDAC-IN-61 HDAC
HDAC-IN-61 (compound 12k) is a potent, orally active inhibitor of histone deacetylase (HDAC) with anticancer activity, exhibiting an IC50 of 30 nM against Bel-7402 cells, and is utilized for cancer research [1].
T13643 Demethoxydeacetoxypseudolaric acid B analog Others
Demethoxydeacetoxypseudolaric acid B analog has potent activities against HMEC-1, HL-60, A-549, MB-MDA-468, BEL-7402, HCT116, and Hela cells with IC50s ranging from 0.136 to 1.162 μM. and is semi-synthesized by efficient...
TN3646 Chlorovaltrate K Others
Chlorovaltrate K shows moderate cytotoxicity against lung adenocarcinoma (A 549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8) and hepatoma (Bel 7402) cell lines with IC50 values of 0.89-9.76 uM.
T82741 Changnanic acid
Changnanic acid (schisandrin), a triterpene compound, has demonstrated potential anti-tumor properties, exhibiting moderate cytotoxicity against human tumor cell lines Bel-7402 and MCF-7 with IC50s of 100 μM, and against...
TN1646 Flemiphilippinin A Others
Flemiphilippin A has antioxidant activity, it shows DPPH radical scavenging activity with effective half maximal concentration (EC50) of 18.36 ug/mL. Flemiphilippinin A (5 ug/mL) exhibits some level of antitumor activity...
T36882 CAY10773
CAY10773 is a derivative of the ferroptosis inducer sorafenib .1It selectively inhibits proliferation of BEL-7402, MGC803, and T24 bladder cancer cells (IC50s = 5.77, 5.21 and 3.97 μM, respectively) over non-cancerous HC...
T35558 KAAD-Cyclopamine
Cyclopamine-KAAD is a potent inhibitor of hedgehog signaling with an IC50 value of 20 nM in a Shh-LIGHT2 assay. It blocks binding of BODIPY-cyclopamine to cells expressing Smoothened (Smo) in a dose-dependent manner. Cyc...
T36848 Combretastatin A-1 Combretastatin A1 Akt , Microtubule Associated
Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and...
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