Search Result

Search Results for " bp1 "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T1834	CX-6258	CX 6258	Pim
	CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.		Pim
T3058	(Z)-SMI-4a	TCS PIM-1 4a,SMI-4a	Pim
	(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.		Pim
T70948	Sjc 13
	Sjc 13 is an azaindolidine derivative that is a cell adhesion molecule inhibitor.
T4215	TCS-PIM-1-4a	SMI-4a	Apoptosis , Pim
	TCS-PIM-1-4a (SMI-4a), a Pim inhibitor, blocks mTORC1 activity through activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (IC50=0.8-40 μM).		Apoptosis , Pim
T6148	CX-6258 hydrochloride	CX-6258 HCl,Pim-Kinase Inhibitor X	Pim
	CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).		Pim
T11332	FUBP1-IN-1	FUBP1–IN-1	Others
	FUBP1 - in-1, with an IC50 value of 11.0 M, is an effective FUSE binding protein 1 (FUBP1) inhibitor that can interfere with the binding of FUBP1 to its SINGLE-strand target DNA FUSE sequence.		Others
T3973	PF-CBP1		Epigenetic Reader Domain
	PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP). It inhibits CREBBP (IC50: 125 nM) and p300 bromodomains (IC50: 363 nM).		Epigenetic Reader Domain
T3969	I-CBP112		Epigenetic Reader Domain , Histone Acetyltransferase
	I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.		Epigenetic Reader Domain , Histone Acetyltransferase
T26890	BP14979	BP 14979,BP1,4979,BP-14979,BP 1,4979,BP-1,4979
	BP14979 is D3R-selective partial agonist.
T7321	MBP146-78		Parasite
	MBP146-78 is a potent and selective cGMP inhibitor dependent protein kinases.		Parasite
T3217	PF-CBP1 hydrochloride	PF-CBP1 HCl	Epigenetic Reader Domain , Histone Acetyltransferase
	PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.		Epigenetic Reader Domain , Histone Acetyltransferase
T4247	I-CBP112 hydrochloride		Epigenetic Reader Domain
	I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly re...		Epigenetic Reader Domain
T29036	UBP141	UBP 141,UBP-141
	UBP141 is a antagonist of N-methyl-D-aspartate (NMDA) receptor.
T83742	SBP1 TFA	Spike Binding Peptide 1
	Spike Binding Peptide 1 (SBP1), representing amino acids 21-43 of angiotensin-converting enzyme 2 (ACE2), has been utilized in a novel approach involving lipid nanoparticles (LNPs) encapsulated with oseltamivir phosphate...
T81356	PTBP1-RNA-binding inhibitor P6 TFA	PTBP1 α3-helix derived peptide P6 TFA
	PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide that acts as an inhibitor for the splicing factor PTBP1, targeting the alternative splicing events this protein regulates. It op...
T73166	FUBP1-IN-2
	FUBP1-IN-2 is a potent inhibitor of far upstream binding protein 1 (FUBP1), effectively disrupting the FUBP1-FUSE interaction in the KH4 domain as demonstrated in a gel shift assay. This compound also exhibits binding af...
T79724	IGF2BP1-IN-1
	IGF2BP1-IN-1 (Compound A11), an inhibitor of IGF2BP1, impedes the associated downstream signaling and demonstrates a high affinity for the IGF2BP1 protein with a dissociation constant (K D) of 2.88 nM. The compound effec...
T36877	SBP1-FITC	SBP1-FITC
	Fluorescently labelled peptide derived from human ACE2 (SBP1, Cat. No. 7233). Composed of SBP1 conjugated to FITC (Fluorescein-5-isothiocyanate; Cat. No. 5440). SBP1 binds receptor binding domain (RBD) of insect-derived ...
T36876	SBP1
	Human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et a...
T11291	FKBP12 PROTAC dTAG-13	dTAG-13	Epigenetic Reader Domain
	FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcription...		Epigenetic Reader Domain
TP1948	PBP10	PBP 10
	Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro...
T81357	PTBP1 α3-helix derived peptide P1 TFA
	PTBP1α3-helix derived peptide P1 is a polypeptide that impedes RNA binding [1].
T71840	FKBP12-IN-Q2
	FKBP12-IN-Q2 is an inhibitor of FKBP12.
T23491	UBP1112		Others
	group III mGlu receptor antagonist		Others
T81279	RhB-PBP10 TFA
	RhB-PBP10 TFA, a Rhodamine B-labeled PBP10 TFA (FPR2 antagonist), selectively inhibits granule mobilization and oxygen radical secretion in FPRL1-induced neutrophils [1].
T11292	FKBP12 PROTAC dTAG-7	dTAG-7	Epigenetic Reader Domain
	FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by connecting BET bromodomains to the E3 ubiquitin ligase CRBN. Additionally,...		Epigenetic Reader Domain
T13694	FKBP12 PROTAC RC32	RC32	Others
	FKBP12 PROTAC RC32 contains conjugation of Rapamycin and a ligand for an E3 ubiquitin ligase.FKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader based on PROTAC technology.		Others
T75811	PBP10 TFA
	PBP10, a cell-permeable and selective gelsolin-derived peptide, inhibits formyl peptide receptor 2 (FPR2) over FPR1 [1]. This 10-amino acid (AA) peptide features a rhodamine conjugation at its N terminus, exhibiting bact...
T25171	BP13944	BP 13944,BP-13944
	BP13944 is used as a potential dengue virus NS2B/NS3 protease inhibitor.
T33893	PBP1	PBP-1,PBP 1
	PBP1 is a selective inducer of i-motif structures from the unstructured single-stranded DNA conformations which upregulates BCL-2 gene expression in cancer cells.
T9229	Pim-1/2 kinase inhibitor 1		Pim
	Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim ...		Pim
T1742	4E1rcat		PERK , Autophagy
	4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.		PERK , Autophagy
T39958	(32-Carbonyl)-RMC-5552
	(32-Carbonyl)-RMC-5552 is a highly effective mTOR inhibitor, exhibiting inhibitory effects on both mTORC1 and mTORC2 substrate phosphorylation. Specifically, it significantly suppresses the phosphorylation of p-P70S6K-(T...
T39776	RMC-4529
	RMC-4529 is a chemical compound that demonstrates potent inhibition, with an IC50 value of 1.0 nM, against p-4E-BP1-(T37/46) in mTOR kinase cellular assays.

Compounds

Synonym: TCS PIM-1 4a,SMI-4a

Target: Apoptosis, Pim

CX-6258 hydrochloride

T6148

Synonym: CX-6258 HCl,Pim-Kinase Inhibitor X

Target: Epigenetic Reader Domain

I-CBP112

T3969

Synonym:

Target: Epigenetic Reader Domain, Histone Acetyltransferase

BP14979

T26890

Synonym: BP 14979,BP1,4979,BP-14979,BP 1,4979,BP-1,4979

PF-CBP1 hydrochloride

T3217

Synonym: PF-CBP1 HCl

Target: Epigenetic Reader Domain, Histone Acetyltransferase

I-CBP112 hydrochloride

T4247

Synonym:

Target: Epigenetic Reader Domain

UBP141

T29036

Synonym: UBP 141,UBP-141

Target:

SBP1 TFA

T83742

Synonym: Spike Binding Peptide 1

Target:

PTBP1-RNA-binding inhibitor P6 TFA

T81356

Synonym: PTBP1 α3-helix derived peptide P6 TFA

FKBP12 PROTAC dTAG-13

T11291

Synonym: dTAG-13

Target: Epigenetic Reader Domain

PTBP1 α3-helix derived peptide P1 TFA

Target: Epigenetic Reader Domain

Synonym: BP 13944,BP-13944

Pim-1/2 kinase inhibitor 1

Target: PERK, Autophagy

(32-Carbonyl)-RMC-5552

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01769	4EBP1 Protein, Human, Recombinant (His)	Human	E. coli
	The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip...
TMPY-02444	ATF2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac...
TMPK-00729	Siglec-6 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by ...
TMPY-03864	CRABP1 Protein, Human, Recombinant	Human	E. coli
	CRABP1 is a specific binding protein for a vitamin A family member. It is thought that CRABP1 plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar ...
TMPY-00146	RKIP/PEBP1 Protein, Human, Recombinant	Human	E. coli
	Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that mon...
TMPH-00106	TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)	Arabidopsis thaliana	E. coli
	General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a ro...
TMPH-01998	G3BP1 Protein, Human, Recombinant (His)	Human	E. coli
	G3BP1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-03456	SRFBP1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in th...
TMPY-03385	FKBP14 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FKBP14 belongs to the FK506-binding protein family. It contains 2 EF-hand domains and one PPIase FKBP-type domain. FKBP14 can be detected in the lumen of the endoplasmic reticulum where it is thought to accelerate the fo...
TMPY-00510	FKBP11 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	FKBP11 serve as biomarker and/or therapeutic target for Acute aortic dissection (AAD). FKBP11 during the development of HCC and FKBP11 has the potential to be an early marker for HCC.
TMPH-02494	AEBP1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	AEBP1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.8 kDa and the accession number is Q640N1.
TMPJ-01328	ZBP1 Protein, Human, Recombinant (His)	Human	E. coli
	Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of vir...
TMPH-02702	HEBP1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	HEBP1 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-02166	STXBP1 Protein, Human, Recombinant	Human	E. coli
	Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machiner...
TMPY-01820	Munc18-1/STXBP1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Syntaxin-binding protein 1, also known as N-Sec1, Protein unc-18 homolog 1, MUNC18-1 and STXBP1, is a peripheral membrane protein that belongs to the STXBP / unc-18 / SEC1 family. STXBP1 is an evolutionally conserved neu...
TMPH-00407	PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO)	Clostridium botulinum	E. coli
	PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-00814	RBP1 Protein, Human, Recombinant	Human	E. coli
	RBP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14 KDa and the accession number is P09455.
TMPH-03046	TBP1 Protein, MenB, Recombinant (His & Myc)	MenB	E. coli
	Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Binds both apo- and holo-TF, via the TF C-terminus.
TMPH-02403	JBP1 Protein, Leishmania infantum, Recombinant (His & V5)	Leishmania infantum	E. coli
	JBP1 Protein, Leishmania infantum, Recombinant (His & V5) is expressed in E. coli expression system with N-10xHis-V5 tag. The predicted molecular weight is 53.4 kDa and the accession number is A4HU70.
TMPH-02165	STXBP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machiner...
TMPY-01595	PCBP1 Protein, Human, Recombinant (His)	Human	E. coli
	Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that...
TMPY-00559	GPIHBP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GPIHBP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is Q8IV16.
TMPY-00140	ABP1/AOC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putres...
TMPY-02844	EBP1 Protein, Human, Recombinant (His)	Human	E. coli
	EBP1, also known as PA2G4, is an RNA-binding protein that belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-riboso...
TMPH-01888	PTBP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PTBP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 63.1 kDa and the accession number is P26599?.
TMPH-00701	PBP1b Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-...
TMPH-03044	PBP1a Protein, MenB, Recombinant (His & SUMO)	MenB	E. coli
	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-...
TMPH-01786	NCBP1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	NCBP1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 95.7 kDa and the accession number is Q09161.
TMPH-01785	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 99.3 kDa and the accession number is Q09161.
TMPH-03737	ABP1 Protein, Zea mays, Recombinant (His)	Zea mays	E. coli
	Receptor for the plant hormone auxin.
TMPH-02703	HEBP1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	HEBP1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293.
TMPY-00557	GPIHBP1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	GPIHBP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is Q8IV16.
TMPY-00808	FKBP12 Protein, Human, Recombinant (His)	Human	E. coli
	FKBP12 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.9 kDa and the accession number is P62942.
TMPJ-01272	WBP1 Protein, Human, Recombinant (His)	Human	E. coli
	WW Domain-Binding Protein 1 (WBP1) is widely expressed in many tissues, but it is lowly expressed in the lung, placenta, kidney, and liver. WBP1 contains two WW-binding motifs: WW-binding 1 and WW-binding 2 that are invo...
TMPY-03283	HBP1 Protein, Human, Recombinant (GST)	Human	E. coli
	HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16(INK4A) promoter and activates p16(INK4A) expression. We found that trichos...
TMPY-01662	FKBP12 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	FKBP12 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.7 kDa and the accession number is P26883.
TMPY-02549	GBP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 ex...
TMPJ-01386	STUB1 Protein, Human, Recombinant	Human	E. coli
	E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its ...