andrographolide — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2898	Andrographolide	Andrographis	SARS-CoV , Influenza Virus , NF-κB , Autophagy
	Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.		SARS-CoV , Influenza Virus , NF-κB , Autophagy
TQ0185	14-Deoxy-11,12-didehydroandrographolide	AP10,14-dehydro Andrographolide	NF-κB
	14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.		NF-κB
T3884	Neoandrographolide	Neoandrographiside	NOS , COX
	Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iN...		NOS , COX
T2738	Dehydroandrographolide		NOS , Influenza Virus
	Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.		NOS , Influenza Virus
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
	Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.		IL Receptor , TNF
T125901	14-Epiandrographolide
	14-Epiandrographolide is a compound derived from the above-ground parts of Andrographis paniculata that induces cell differentiation and can be used in the study of multiple sclerosis.
T8288	14-Deoxyandrographolide		Apoptosis , Others
	14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.		Apoptosis , Others
T2S0257	Dehydroandrographolide succinate		Others , Influenza Virus
	Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection.		Others , Influenza Virus
TN5586	14-Deoxy-12-hydroxyandrographolide
	14-Deoxy-12-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN5586 and the CAS number is 219721-33-2. 14-Deoxy-12-hydroxyandrographolide can be used as a reference standard...
T72580	Isoandrographolide
	Isoandrographolide, a compound known for its cell differentiation-inducing and hepatoprotective effects, also inhibits NLRP3 inflammasome activation and mitigates silicosis in mice.
TN3518	Bisandrographolide A		Others
	Bisandrographolide A activates TRPV4 channels, could play a role in some of the effects of Andrographis extract described in traditional medicine.		Others
T13582	Bisandrographolide C		Others
	Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury.		Others
TN2623	14-Deoxy-17-hydroxyandrographolide		Antifection
	14-Deoxy-17-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN2623 and the CAS number is 869384-82-7. 14-Deoxy-17-hydroxyandrographolide can be used as a reference standard...		Antifection
TN5585	14-Deoxy-11-hydroxyandrographolide
	14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.
TN2463	14-Deoxy-11-oxoandrographolide		Others
	14-Deoxy-11-oxoandrographolide is a natural product from Andrographis paniculata		Others
T40971	Dehydroandrographolide succinate potassium sodium salt
	Dehydroandrographolide succinate (potassium sodium salt), derived from the herbal medicine Andrographis paniculata (Burm f) Nees, is a versatile compound highly utilized for the treatment of viral pneumonia and viral upp...
T73292	ZIKV-IN-3
	ZIKV-IN-3, a derivative of andrographolide, serves as a potent inhibitor of the Zika virus (ZIKV) NS5 methyl transferase (MTase), showcasing an IC50 of 18.34 μM. It effectively curtails ZIKV replication and infection, ma...
T74895	Anti-inflammatory agent 31
	Anti-inflammatory agent 31 (enone 17), an andrographolide derivative, acts as an anti-inflammatory agent by inhibiting NF-κB activation through the upstream blockade of PI3K/Akt and ERK1/2 MAPK pathways. It effectively r...