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Cat No. | Product Name | Synonyms | Targets |
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T80530 | Spinoxin | SPX,α-KTx6.13,Potassium channel toxin alpha-KTx 6.13 | Potassium Channel |
Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges. It acts as a potent inhibitor of the Kv1.3 potassium channel with an IC 50 value of... | |||
T22297 | Clindamycin hydrochloride monohydrate | Clindamycin alcoholate | Antibiotic |
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentra... | |||
T13540 | alpha-Amanitin | α-Amanitin,α-Amatoxin | Others |
alpha-Amanitin is the principal toxin of poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II. | |||
T82949 | Atidortoxumab | ||
Atidortoxumab is a human monoclonal antibody (IgG1κ) targeting Staphylococcus aureus alpha toxin [1]. | |||
T81832 | MC-VC-PABC-C6-alpha-Amanitin | ||
MC-VC-PABC-C6-alpha-Amanitin is an antibody-drug conjugate that combines the anticancer toxin alpha-Amanitin with the monoclonal antibody MC-VC-PABC-C6. Alpha-Amanitin acts as a potent inhibitor of RNA polymerase IIα, en... | |||
T80482 | α-Conotoxin EIIB | Alpha-conotoxin EIIB | |
Alpha-Conotoxin EIIB is a peptide toxin derived from Conus ermineus that selectively binds to neuronal nicotinic acetylcholine receptors (nAChR) with a dissociation constant (Ki) of 2.2 nM. This compound is utilized in n... | |||
T80034 | Margatoxin TFA | Potassium Channel | |
Margatoxin TFA, an alpha-KTx scorpion toxin isolated from Centruroides margaritatus venom, is a 39-amino-acid peptide that serves as a high-affinity inhibitor of Kv1.3 (Kd = 11.7 pM). It also inhibits Kv1.2 (Kd = 6.4 pM)... | |||
T76973 | Tosatoxumab | ||
Tosatoxumab (AR-301; KBSA301), a human immunoglobulin G1 monoclonal antibody, specifically targets and neutralizes S. aureus alpha-toxin (alpha-hemolysin; Hla) by binding to its N-terminal epitope. This interaction block... |
Cat No. | Product Name | Species | Expression System |
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TMPH-03522 | Alpha-hemolysin Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | P. pastoris (Yeast) |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl... | |||
TMPH-03523 | Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl... | |||
TMPH-00054 | AaH II Protein, Androctonus australis, Recombinant (His & SUMO) | Androctonus australis | E. coli |
AaH II Protein, Androctonus australis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 23.3 kDa and the accession number is P01484. | |||
TMPH-00837 | BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc) | Hottentotta judaicus | E. coli |
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against insects (para/tipE).... | |||
TMPH-03625 | Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) | Tityus serrulatus | Baculovirus Insect Cells |
Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 10.9 kDa and the accession number is P684... | |||
TMPH-00055 | Alpha-toxin Amm8 Protein, Androctonus mauritanicus, Recombinant (His & Myc) | Androctonus mauritanicus | Baculovirus Insect Cells |
Alpha-toxin Amm8 Protein, Androctonus mauritanicus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 11.3 kDa and the accession number is Q7... | |||
TMPH-00430 | VxXIIC Protein, Conus vexillum, Recombinant (His & Myc & SUMO) | Conus vexillum | E. coli |
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-bet... | |||
TMPK-01058 | GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain... | |||
TMPK-01060 | GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain... | |||
TMPK-01319 | GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi) | Cynomolgus | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain... | |||
TMPK-01053 | GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain... | |||
TMPK-01059 | GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain... | |||
TMPK-01052 | GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain... | |||
TMPK-01320 | GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated | Cynomolgus | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain... | |||
TMPH-03652 | Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) | UmV6 | P. pastoris (Yeast) |
This protein is lethal to sensitive cells of the same or related species. The KP6 alpha subunit is known to recognize some cellular receptors before interaction of the complex with KP6 beta, precipitating cell death. Ust... | |||
TMPH-02404 | LqhaIT Protein, Leiurus hebraeus, Recombinant (His & SUMO) | Yellow scorpion | E. coli |
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The dissociation is voltage-dependent. This toxin... | |||
TMPY-00583 | ADPRH Protein, Human, Recombinant (His) | Human | E. coli |
Cholera toxin (CT) produced by Vibrio cholerae causes the devastating diarrhea of cholera by catalyzing the ADP-ribosylation of the alpha subunit of the intestinal Gs protein (Gsalpha), leading to characteristic water an... | |||
TMPY-02246 | HB-EGF Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolyticall... |