apc — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15641	K777	APC-3316	P450 , Cysteine Protease , CCR
	K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 ...		P450 , Cysteine Protease , CCR
T69182	APC-3316 hydrochloride
	APC-3316 hydrochloride is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.
T39029	APC-6860
	APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA ve...
T40081	APC 366 TFA
	APC 366 (TFA) is a potent irreversible inhibitor of mast cell tryptase. It is particularly useful in studies related to allergic diseases.
T38466	4-APC hydrobromide
	4-APC hydrobromide is a potent and specific aldehyde derivatization agent. It contains an aniline moiety that enables rapid and selective reaction with aliphatic aldehydes, as well as a quaternary ammonium group that enh...
T22189	APC 366
	APC 366 is a selective inhibitor of mast cell tryptase with Ki of 7.1 μM. APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep...
T30094	APC-6336	UNII-4124YUO44Z,CRA-6336,4124YUO44Z
	APC-6336 is a bio-active chemical.
T69453	APC-0576
	APC-0576 is an (S,S)-isomer which inhibits NF-kappaB-dependent gene activation. APC-0576 may prevent pro-inflammatory cytokine-induced chemokine production in human endothelial cells.
T12766	RPR121056	APC	AChR
	RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.		AChR
T69183	APC-3316 tosylate
	APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.
T70193	APC-366 HCl
	APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.
T8561	Apcin		APC
	Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substr...		APC
T70192	NC-2100
	NC-2100 is an aperoxisome proliferator-activated receptor-gamma (PPARgamma) activator.
T22884	JW 67		Wnt/beta-catenin
	JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.		Wnt/beta-catenin
T12575	Unesbulin	PTC596	Apoptosis , BMI-1
	Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).		Apoptosis , BMI-1
T1731	TAME hydrochloride	Tos-Arg-OMe HCl,TOS-ARG-OME hydrochloride	Amino Acids and Derivatives , APC
	TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.		Amino Acids and Derivatives , APC
T6693	TAME	Tosylarginine methyl ester,N-4-Tosyl-L-arginine methyl ester	APC
	Tosyl-L-Arginine Methyl Ester (TAME (N-4-Tosyl-L-arginine methyl ester)) is an APC inhibitor.		APC
T64339	Apcin A HCL		APC
	Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to...		APC
T74235	DHAPC
	DHAPC is a phospholipid that is very sensitive to oxidation [1] .
T10345	Apcin-A		Others
	Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.		Others