8
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1477 | AICAR | NSC105823,AICA Riboside,Acadesine,AICAR (Acadesine) | Mitophagy , YAP , AMPK , Autophagy |
AICAR (NSC105823) is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes. | |||
T21195 | AICAR monophosphate | Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide | Others |
AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes. | |||
T14149 | AICAR phosphate | AICA Riboside phosphate,Acadesine phosphate | Mitophagy , NOS , YAP , AMPK |
AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose and lipid metabolism, and inhibits the production of pro-in... | |||
T16837 | SAICAR | Others | |
SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM). | |||
TP2312 | MOTS-c(Human) Acetate(1627580-64-6 free) | Others , AMPK | |
MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate ind... | |||
T76039 | MOTS-c(human) acetate | ||
MOTS-c(human) acetate, a mitochondrial-derived peptide, induces the accumulation of AMP analog AICAR, enhances AMPK activation, and upregulates its downstream target, GLUT4. This compound promotes glucose uptake and enha... | |||
T78159 | ATIC-IN-1 acetate | Others | |
ATIC-IN-1 (compound 14) acetate is an ATIC dimerization inhibitor with a K i value of 685 nM, essential for AICAR transformylase activity. It demonstrates anti-tumor effects by decreasing cell proliferation and division ... | |||
T82950 | ATIC-IN-1 | ||
ATIC-IN-1 (compound 14) serves as an inhibitor specifically aimed at the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This di... |