keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 90.00 | |
5 mg | In stock | $ 170.00 | |
10 mg | In stock | $ 243.00 | |
25 mg | In stock | $ 437.00 | |
50 mg | In stock | $ 607.00 | |
100 mg | In stock | $ 863.00 | |
500 mg | In stock | $ 1,760.00 |
Description | MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity. |
In vitro | MOTS-c inhibits the folate cycle at the level of 5Me-THF, resulting in an accumulation of AICAR [5-aminoimidazole-4-carboxamide ribonucleotide). MOTS-c also increases cellular NAD+ levels, which are also nucleotide precursors[1]. |
In vivo | MOTS-c injections in mice show activation of skeletal muscle AMPK and increased the level of its downstream glucose transporter GLUT4. MOTS-c may also act as a potential mitochondrial signal that mediates an exercise-induced mitohormesis response, thereby stimulating physiological adaptation and increased tolerance to exercise[1]. |
Molecular Weight | 2234.64 |
Formula | C103H156N28O24S2 |
CAS No. | TP2312 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. More
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MOTS-c(Human) Acetate(1627580-64-6 free) TP2312 Chromatin/Epigenetic Others PI3K/Akt/mTOR signaling AMPK 1627580-64-6 free MOTSc(Human) Acetate(1627580646 free) MOTS c(Human) Acetate(1627580 64 6 free) MOTS-c(Human) Acetate inhibitor inhibit