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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1045 | Trimipramine maleate | Surmontil maleate | Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal... | |||
T4369 | SCH-23390 hydrochloride | R-(+)-SCH23390 hydrochloride | Potassium Channel , Dopamine Receptor , 5-HT Receptor |
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM). | |||
T12865 | SCH-23390 maleate | R-(+)-SCH-23390 maleate | Potassium Channel , Dopamine Receptor , 5-HT Receptor |
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, respectively). | |||
T22689 | CP94253 hydrochloride | CP 94253 hydrochloride | Others , 5-HT Receptor |
CP94253 hydrochloride (CP 94253 hydrochloride) is a potent, selective and centrally active agonist of 5-HT1B receptor with Ki of 2 nM. The Kis are 89, 49, 860, and 1600 nM for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors, ... | |||
T21855 | AMI-193 | Espiramida,Spiramide | Dopamine Receptor , 5-HT Receptor |
AMI-193 (Spiramide) is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 Receptor, and 5-HT1C Receptor. AMI-193 shows antipsychotic ... | |||
T5389 | Volinanserin | M 100907,MDL100907 | 5-HT Receptor |
Volinanserin (MDL100907) (MDL 100907) is a potent and selective antagonist of the serotonin receptor 5-HT2 (Ki: 0.36 nM) and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 adrenergic and sigma recepto... | |||
T0225 | Pizotifen Malate | Pizotyline (malate),BC-105 (malate),BC-105 | 5-HT Receptor |
Pizotifen Malate (BC-105 malate), a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane. | |||
T22987 | MK 212 hydrochloride | 5-HT Receptor | |
MK 212 hydrochloride is a 5-HT2C receptor agonist | |||
T1442 | Pizotifen | Pizotyline,BC-105 | 5-HT Receptor |
Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydroch... | |||
T28637 | S 14506 HCl | S14506 HCl,S-14506,S14506HCl | |
S 14506 HCl is a highly potent selective 5-HT1A receptor full agonist, pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively. | |||
T27574 | ZM 169369 | ICI169369,ICI-169369 | |
ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta. | |||
T3046 | BMY 7378 dihydrochloride | BMY7378 HCl | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor. |