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Search Result

Search Results for " 5-ht7 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10170 5-HT7 agonist 1 4-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-1H-indole,4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole,4-[4-(2-chlorobenzyl)piperazino]-1H-indole 5-HT Receptor
5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM). 5-HT7 agonist 1 can be used in studies about CNS disorders.
T61375 5-HT7 agonist 2
5-HT7 agonist 2 is a highly potent 5-HT7 receptor agonist, exhibiting an IC50 value of 28.7 nM. This compound holds promise for studying and understanding various Central Nervous System (CNS) disorders [1].
T61515 5-HT7 receptor ligand 1
5-HT7 receptor ligand 1 (Compound 5c) is a potent ligand for the 5-HT7 receptor, with a K i value of 8 nM. The compound demonstrates non-hepatotoxic properties and displays moderate potential for drug-drug interactions w...
T12855 SB 258719 5-HT Receptor
SB 258719 is a selective antagonist of 5-HT7 receptor(pKi of 7.5).
T6655 SB-269970 hydrochloride SB-269970A,SB269970 HCl 5-HT Receptor
SB-269970 hydrochloride (SB-269970A) , a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity against other receptors.
T11720 JNJ-18038683 5-HT Receptor
JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.
T26375 (S)-Amisulpride Esamisulpride,(S) Amisulpride,SEP-4199 Dopamine Receptor , 5-HT Receptor
(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a Ki of 900 nM. (S)-Amisulpride has antipsychotic and antidepr...
T5387 LP-211 Dopamine Receptor , 5-HT Receptor
LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
T21337 Lurasidone SM-13496 Dopamine Receptor , 5-HT Receptor
Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6.75 nM).
T23396 ST1936 ST 1936 oxalate 5-HT Receptor
ST1936 (ST 1936 oxalate) is a selective and highly potent 5-HT6 receptor agonist that inhibits human 5-HT6, 5-HT7 and 5-HT2B receptors by fully activating cloned human 5-HT6 receptors. body to stimulate cAMP, Ca2+, ERK1/...
T14782 Brilaroxazine RP5063 Dopamine Receptor , 5-HT Receptor
Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-...
T1735 Lurasidone hydrochloride Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496 Dopamine Receptor , 5-HT Receptor , Norepinephrine
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antag...
T11326 Frovatriptan succinate hydrate Frovelan,Frova 5-HT Receptor
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also b...
T24885 Tiospirone BMY 13859-1 Dopamine Receptor , 5-HT Receptor
Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia.
T26690 AVN-101 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
AVN-101 is a potent 5-HT7 receptor antagonist.
T4305 8-OH-Dpat 8-Hydroxy-DPAT 5-HT Receptor
8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
T2395L Vortioxetine hydrobromide Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,Lu AA21004 hydrobromide 5-HT Receptor , Serotonin Transporter
Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
T2395 Vortioxetine Lu AA 21004 5-HT Receptor , Serotonin Transporter
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.
T3369 Nuciferine (-)-Nuciferine,VLT 049,Sanjoinine E Dopamine Receptor , 5-HT Receptor
Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade.
T4118 SB 271046 hydrochloride SB 271046A 5-HT Receptor
SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and ...

Compounds

5-HT7 agonist 1
T10170
Synonym: 4-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-1H-indole,4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole,4-[4-(2-chlorobenzyl)piperazino]-1H-indole
Target: 5-HT Receptor
5-HT7 agonist 2
T61375
Synonym:
Target:
5-HT7 receptor ligand 1
T61515
Synonym:
Target:
SB 258719
T12855
Synonym:
Target: 5-HT Receptor
SB-269970 hydrochloride
T6655
Synonym: SB-269970A,SB269970 HCl
Target: 5-HT Receptor
JNJ-18038683
T11720
Synonym:
Target: 5-HT Receptor
(S)-Amisulpride
T26375
Synonym: Esamisulpride,(S) Amisulpride,SEP-4199
Target: Dopamine Receptor, 5-HT Receptor
LP-211
T5387
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Lurasidone
T21337
Synonym: SM-13496
Target: Dopamine Receptor, 5-HT Receptor
ST1936
T23396
Synonym: ST 1936 oxalate
Target: 5-HT Receptor
Brilaroxazine
T14782
Synonym: RP5063
Target: Dopamine Receptor, 5-HT Receptor
Lurasidone hydrochloride
T1735
Synonym: Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496
Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine
Frovatriptan succinate hydrate
T11326
Synonym: Frovelan,Frova
Target: 5-HT Receptor
Tiospirone
T24885
Synonym: BMY 13859-1
Target: Dopamine Receptor, 5-HT Receptor
AVN-101
T26690
Synonym:
Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
8-OH-Dpat
T4305
Synonym: 8-Hydroxy-DPAT
Target: 5-HT Receptor
Vortioxetine hydrobromide
T2395L
Synonym: Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,Lu AA21004 hydrobromide
Target: 5-HT Receptor, Serotonin Transporter
Vortioxetine
T2395
Synonym: Lu AA 21004
Target: 5-HT Receptor, Serotonin Transporter
Nuciferine
T3369
Synonym: (-)-Nuciferine,VLT 049,Sanjoinine E
Target: Dopamine Receptor, 5-HT Receptor
SB 271046 hydrochloride
T4118
Synonym: SB 271046A
Target: 5-HT Receptor
1 2 3
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