T Cell CD Proteins

T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature).After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus.CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from "self".

Cat No.	product name / Synonyms	Species	Expression System
TMPK-00544	TLR3 Protein, Cynomolgus, Recombinant (His) TLR3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-00544	TLR3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.04 kDa and the accession ...
TMPK-00591	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)	Mouse	HEK293 Cells
TMPK-00591	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s...
TMPK-00642	CD5 Protein, Rhesus macaque, Recombinant (His & Avi) CD5 Protein, Rhesus macaque, Recombinant (His & Avi)	Rhesus	HEK293 Cells
TMPK-00642	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ...
TMPK-00643	CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated	Rhesus	HEK293 Cells
TMPK-00643	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ...
TMPK-00653	B7-2 Protein, Cynomolgus, Recombinant (His) B7-2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-00653	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00688	PD-1 Protein, Canine, Recombinant (aa 25-170, hFc) PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)	Canine	HEK293 Cells
TMPK-00688	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp...
TMPK-00694	CD1A Protein, Human, Recombinant (His) CD1A Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPK-00694	CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tai...
TMPK-00716	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)	Human	HEK293 Cells
TMPK-00716	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s...
TMPK-00717	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
TMPK-00717	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s...
TMPK-00860	CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc) CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)	Mouse	HEK293 Cells
TMPK-00860	CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b...
TMPK-00880	B7-2 Protein, Human, Recombinant (His & Avi) B7-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00880	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00881	B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00881	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00882	B7-2 Protein, Human, Recombinant (hFc) B7-2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00882	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul...
TMPK-00955	CD161 Protein, Human, Recombinant (His & Avi), Biotinylated CD161 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00955	CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leu...
TMPK-00956	CD161 Protein, Human, Recombinant (His) CD161 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPK-00956	CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leu...
TMPK-01135	CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (His) CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-01135	CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cel...
TMPK-01136	CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293 Cells
TMPK-01136	CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cel...
TMPK-01176	CD28 Protein, Canine, Recombinant (His) CD28 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
TMPK-01176	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present...
TMPK-01177	CD28 Protein, Canine, Recombinant (mFc) CD28 Protein, Canine, Recombinant (mFc)	Canine	HEK293 Cells
TMPK-01177	CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present...
TMPK-01230	CLEC2D Protein, Human, Recombinant (hFc & Avi) CLEC2D Protein, Human, Recombinant (hFc & Avi)	Human	HEK293 Cells
TMPK-01230	C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contra...