T Cell CD Proteins

T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature).After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus.CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from "self".

Cat No.	product name / Synonyms	Species	Expression System
TMPK-00192	B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi) B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00192	B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulat...
TMPK-00193	B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00193	B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulat...
TMPK-00281	CD4 Protein, Human, Recombinant (His & Avi) CD4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00281	CD4, also known as L3T4, T4, and W3/25, is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset o...
TMPK-00282	CD4 Protein, Human, Recombinant (aa 26-390, His & Avi), Biotinylated CD4 Protein, Human, Recombinant (aa 26-390, His & Avi), Biotinylated	Human	HEK293
TMPK-00282	CD4, also known as L3T4, T4, and W3/25, is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset o...
TMPK-00289	IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi) IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00289	The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoprotein...
TMPK-00300	CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
TMPK-00300	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ...
TMPK-00301	CD5 Protein, Human, Recombinant (hFc & Avi) CD5 Protein, Human, Recombinant (hFc & Avi)	Human	HEK293
TMPK-00301	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ...
TMPK-00302	CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
TMPK-00302	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ...
TMPK-00316	IL-18R alpha Protein, Human, Recombinant (His & Avi) IL-18R alpha Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00316	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (I...
TMPK-00317	IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00317	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (I...
TMPK-00346	CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi) CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00346	The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted ...
TMPK-00377	DPPIV/CD26 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) DPPIV/CD26 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus macaque	HEK293
TMPK-00377	CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longst...
TMPK-00406	TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293
TMPK-00406	TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TL...
TMPK-00423	CD45 Protein, Human, Recombinant (His & Avi) CD45 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00423	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck,...
TMPK-00424	CD45 Protein, Human, Recombinant (His & Avi), Biotinylated CD45 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00424	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck,...
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc) CD45 Protein, Human, Recombinant (aa 26-577, hFc)	Human	HEK293
TMPK-00447	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck,...
TMPK-00463	OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi) OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293
TMPK-00463	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molec...
TMPK-00464	OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
TMPK-00464	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molec...
TMPK-00500	CD83 Protein, Cynomolgus, Recombinant (His) CD83 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00500	CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety o...
TMPK-00512	IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)	Cynomolgus	HEK293
TMPK-00512	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (I...