T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature).After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus.CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from "self".
Cat No. | product name / Synonyms | Species | Expression System |
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TMPK-00107 | NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled
NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled
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Human | HEK293 |
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ... | |||
TMPK-00108 | NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)
NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)
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Human | HEK293 |
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ... | |||
TMPK-00110 | CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)
CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)
|
Human,Cynomolgus,Rhesus macaque | HEK293 |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-00111 | CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated
CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated
|
Human,Cynomolgus,Rhesus macaque | HEK293 |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-00112 | CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated
CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 |
CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune ... | |||
TMPK-00122 | CD30 Ligand/TNFSF8 Protein, Human, Recombinant (His)
CD30 Ligand/TNFSF8 Protein, Human, Recombinant (His)
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Human | HEK293 |
CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, ... | |||
TMPK-00123 | CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated
CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated
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Human | HEK293 |
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing... | |||
TMPK-00147 | 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi)
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi)
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Human | HEK293 |
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but ... | |||
TMPK-00148 | 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated
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Human | HEK293 |
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but ... | |||
TMPK-00154 | CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
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Human | HEK293 |
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b... | |||
TMPK-00164 | IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)
IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 |
Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of bi... | |||
TMPK-00165 | IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 |
Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of bi... | |||
TMPK-00167 | OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi)
OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molec... | |||
TMPK-00168 | OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated
OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated
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Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molec... | |||
TMPK-00169 | OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
|
Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molec... | |||
TMPK-00170 | CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated
CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated
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Human | HEK293 |
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activate... | |||
TMPK-00178 | B7-1 Protein, Human, Recombinant (His & Avi)
B7-1 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 |
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal ne... | |||
TMPK-00179 | B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated
B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated
|
Human | HEK293 |
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal ne... | |||
TMPK-00180 | PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated
PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated
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Human | HEK293 |
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp... | |||
TMPK-00181 | PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
|
Mouse | HEK293 |
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp... |