T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature).After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus.CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from "self".
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-00215 | Fas/CD95 Protein, Mouse, Recombinant (hFc)
Fas/CD95 Protein, Mouse, Recombinant (hFc)
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Mouse | Human Cells |
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas ... | |||
TMPJ-00223 | SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated
SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | Human Cells |
SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the i... | |||
TMPJ-00226 | SLAMF1 Protein, Mouse, Recombinant (His)
SLAMF1 Protein, Mouse, Recombinant (His)
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Mouse | Human Cells |
Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but al... | |||
TMPJ-00291 | IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
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Human | Human Cells |
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part... | |||
TMPJ-00340 | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
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Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00341 | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
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Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00342 | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
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Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00343 | CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
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Human | Human Cells |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon... | |||
TMPJ-00353 | ILDR2 Protein, Human, Recombinant (His)
ILDR2 Protein, Human, Recombinant (His)
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Human | Human Cells |
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasi... | |||
TMPJ-00419 | CD16b Protein, Human, Recombinant (hFc & His)
CD16b Protein, Human, Recombinant (hFc & His)
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Human | Human Cells |
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3... | |||
TMPJ-00420 | CTLA-4 Protein, Mouse, Recombinant (Flag)
CTLA-4 Protein, Mouse, Recombinant (Flag)
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Mouse | Human Cells |
Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity w... | |||
TMPJ-00422 | OX40/TNFRSF4 Protein, Mouse, Recombinant (His)
OX40/TNFRSF4 Protein, Mouse, Recombinant (His)
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Mouse | Human Cells |
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis o... | |||
TMPJ-00555 | B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
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Human | Human Cells |
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C... | |||
TMPJ-00556 | B7-2 Protein, Human, Recombinant (His)
B7-2 Protein, Human, Recombinant (His)
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Human | Human Cells |
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C... | |||
TMPJ-00630 | B7-1 Protein, Cynomolgus, Recombinant (hFc)
B7-1 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | Human Cells |
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr... | |||
TMPJ-00632 | B7-2 Protein, Cynomolgus, Recombinant (hFc)
B7-2 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | Human Cells |
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo... | |||
TMPJ-00634 | CD40 Protein, Cynomolgus, Recombinant (His)
CD40 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | Human Cells |
CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cel... | |||
TMPJ-00635 | CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | Human Cells |
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with... | |||
TMPJ-00636 | CTLA-4 Protein, Cynomolgus, Recombinant (His)
CTLA-4 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | Human Cells |
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with... | |||
TMPJ-00640 | CTLA-4 Protein, Cavia porcellus, Recombinant (His)
CTLA-4 Protein, Cavia porcellus, Recombinant (His)
|
Cavia porcellus | P. pastoris |
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with... |