T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature).After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus.CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from "self".
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-00641 | B7-2 Protein, Rhesus macaque, Recombinant (His)
B7-2 Protein, Rhesus macaque, Recombinant (His)
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Rhesus macaque | Human Cells |
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo... | |||
TMPJ-00794 | CD45 Protein, Mouse, Recombinant (His)
CD45 Protein, Mouse, Recombinant (His)
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Mouse | Human Cells |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its fun... | |||
TMPJ-00920 | CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
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Mouse | Human Cells |
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino ... | |||
TMPJ-00958 | B7-1 Protein, Rabbit, Recombinant (His)
B7-1 Protein, Rabbit, Recombinant (His)
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Rabbit | Human Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of ... | |||
TMPJ-00959 | B7-2 Protein, Rabbit, Recombinant (His)
B7-2 Protein, Rabbit, Recombinant (His)
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Rabbit | Human Cells |
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo... | |||
TMPJ-01070 | CD83 Protein, Human, Recombinant (hFc)
CD83 Protein, Human, Recombinant (hFc)
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Human | Human Cells |
CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes,... | |||
TMPJ-01094 | CD161 Protein, Human, Recombinant (C-hFc)
CD161 Protein, Human, Recombinant (C-hFc)
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Human | Human Cells |
Killer cell lectin-like receptor subfamily B, member 1(KLRB1) is a single-pass type II membrane protein which contains 1 C-type lectin domain. KLRB1 plays an inh... | |||
TMPJ-01095 | CD161 Protein, Human, Recombinant (N-hFc)
CD161 Protein, Human, Recombinant (N-hFc)
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Human | Human Cells |
Killer cell lectin-like receptor subfamily B, member 1(KLRB1) is a single-pass type II membrane protein which contains 1 C-type lectin domain. KLRB1 plays an inh... | |||
TMPJ-01235 | B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)
B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | Human Cells |
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component... | |||
TMPJ-01236 | B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)
B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)
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Cynomolgus | Human Cells |
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component... | |||
TMPJ-01252 | CLEC2D Protein, Mouse, Recombinant (His)
CLEC2D Protein, Mouse, Recombinant (His)
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Mouse | Human Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is centr... | |||
TMPJ-01259 | CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (aa 22-117, hFc)
CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (aa 22-117, hFc)
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Cynomolgus | Human Cells |
T-cell surface glycoprotein CD3 epsilon chain, also known as CD3E, is a single-pass type I membrane protein. CD3E contains 1 Ig-like (immunoglobulin-like) domain... | |||
TMPJ-01420 | CD40 Protein, Cynomolgus, Recombinant (hFc)
CD40 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | Human Cells |
CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cel... | |||
TMPJ-01458 | OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)
OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | Human Cells |
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis o... | |||
TMPK-00063 | OX40L/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)
OX40L/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)
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Human | HEK293 |
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor fam... | |||
TMPK-00086 | ICOS Protein, Human, Recombinant (aa 21-134, His)
ICOS Protein, Human, Recombinant (aa 21-134, His)
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Human | HEK293 |
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of ... | |||
TMPK-00087 | ICOS Protein, Human, Recombinant (C136S & C137S, His)
ICOS Protein, Human, Recombinant (C136S & C137S, His)
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Human | HEK293 |
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of ... | |||
TMPK-00095 | CD3 epsilon/CD3e 1-27 peptide Protein, Human, Recombinant (hFc & Avi)
CD3 epsilon/CD3e 1-27 peptide Protein, Human, Recombinant (hFc & Avi)
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Human | HEK293 |
CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cel... | |||
TMPK-00105 | NKG2D/CD314 Protein, Human, Recombinant (His & Avi)
NKG2D/CD314 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 |
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ... | |||
TMPK-00106 | NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated
NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 |
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ... |