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ADAM8/CD156a Protein, Mouse, Recombinant (His)

(Synonyms: Ms2, MGC134985, CD156a, Adam8, ADAM 8) Copy Product Info

Synonyms: Ms2, MGC134985, CD156a, Adam8, ADAM 8

Catalog No. TMPK-00933 Copy Product Info
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/CD156a Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 71.7 kDa and the accession number is Q05910.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$56-In Stock
10 μg$88-In Stock
20 μg$1437-10 days7-10 days
50 μg$2787-10 days7-10 days
100 μg$465-In Stock
200 μg$8397-10 days7-10 days
500 μg$1,8507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Description
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/CD156a Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 71.7 kDa and the accession number is Q05910.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberQ05910
ConstructionPro17-Ser658
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22μm filtered solution in 20mM Tris, 5mM CaCl2, 75mM NaCl, 50% Glycerol (pH 7.5).
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsMs2, MGC134985, CD156a, Adam8, ADAM 8
Research Background
Chemical Properties
Molecular Weight71.7 kDa (predicted). 55-70 kDa (Reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: ADAM8/CD156a Protein, Mouse, Recombinant (His) chemical structure | ADAM8/CD156a Protein, Mouse, Recombinant (His) molecular weight