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Complete Freund's adjuvant
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Catalog No. TYD-02820Cas No. 9007-81-2
Alias Complete Freund's adjuvant (CFA)
Complete Freund's adjuvant (CFA) is an emulsified immunostimulant containing mineral oil and heat-killed mycobacteria, capable of inducing Th1 responses and enhancing immune reactions. It is frequently employed in establishing rat models of rheumatoid arthritis and persistent inflammatory pain.
Complete Freund's adjuvant
Complete Freund's adjuvant
Copy Product Info🥰Excellent
Catalog No. TYD-02820Alias Complete Freund's adjuvant (CFA)Cas No. 9007-81-2
Complete Freund's adjuvant (CFA) is an emulsified immunostimulant containing mineral oil and heat-killed mycobacteria, capable of inducing Th1 responses and enhancing immune reactions. It is frequently employed in establishing rat models of rheumatoid arthritis and persistent inflammatory pain.
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| Description | Complete Freund's adjuvant (CFA) is an emulsified immunostimulant containing mineral oil and heat-killed mycobacteria, capable of inducing Th1 responses and enhancing immune reactions. It is frequently employed in establishing rat models of rheumatoid arthritis and persistent inflammatory pain. |
| In vitro | Complete Freund's adjuvant (CFA) is a powerful Th1-type immune response trigger containing various microbial TLR ligands such as TLR 2, 4, and 9 [1]. |
| In vivo | Complete Freund's adjuvant (CFA) releases inflammatory mediators such as TNF-α and IL-6 upon entering the body. These mediators can activate peripheral nerve endings and act on nociceptive nerve terminals, thereby leading to the occurrence of neuropathic pain [2][3]. |
| Synonyms | Complete Freund's adjuvant (CFA) |
| Cas No. | 9007-81-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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