Powder: -20°C for 3 years
In solvent: -80°C for 2 years
YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
Description | YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis. |
In vitro | YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1, and the expression of MMP2 and MMP9. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 inhibits Arp2/3 complex-mediated actin polymerization[1]. |
Synonyms | YH 306, YH306 |
Molecular Weight | 306.36 |
Formula | C19H18N2O2 |
CAS No. | 1373764-75-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 15 mg/mL?(48.96 mM), ultrasonic and adjust pH to 1 with HCl
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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YH-306 1373764-75-0 TRV055 acetate (25849-90-5 Free base) Inhibitor inhibitor inhibit