Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 90.00 | |
5 mg | In stock | $ 163.00 | |
10 mg | In stock | $ 289.00 | |
25 mg | In stock | $ 578.00 | |
50 mg | In stock | $ 788.00 | |
100 mg | In stock | $ 1,120.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 198.00 |
Description | SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity. |
In vitro | SGN-2FF is a fucosylation inhibitor, SGN-2FF inhibits cellular fucosylation by depleting the fucosylation substrate GDP-fucose, and by direct inhibition of fucosyltransferases, and leads to the production of fucosylated glycoproteins including antibodies. SGN-2FF activates human T cells in an antigen-dependent manner. |
In vivo | In multiple mouse tumor models, SGN-2FF exhibits antitumor activity. SGN-2FF shows substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model. |
Molecular Weight | 166.15 |
Formula | C6H11FO4 |
CAS No. | 2089647-47-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 35 mg/mL (210.65 mM), Sonication is recommended.
DMSO: 50 mg/mL (300.93 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SGN-2FF 2089647-47-0 Others SGN 2FF inhibit SGN2FF Inhibitor inhibitor