rock — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13419	ROCK-IN-1		ROCK
	ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological disorders and inflammation-related diseases.		ROCK
T12746	ROCK inhibitor-2		ROCK
	ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).		ROCK
T67748	ROCK-IN-5		ROCK , ERK
	ROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC. ROCK-IN-5 exhibits the potential for cardiac, proliferative and neurodegenerative diseases research.		ROCK , ERK
TQ0110	ROCK-IN-2	TC-S 7001,Azaindole 1	ROCK
	ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.		ROCK
T24723	ROCK-IN-D1	ROCK inhibitor D1,ROCK IN D1,ROCK-inhibitor-D1
	ROCK-IN-D1 is an effective and selective inhibitor of ROCK.
T24724	ROCK-IN-D2	ROCK inhibitor D2,ROCK IN D2,ROCK-inhibitor-D2
	ROCK-IN-D2 is an effective and selective inhibitor of ROCK.
T24722	ROCK-IN-32	ROCK-inhibitor-32,ROCK inhibitor 32
	ROCK-IN-32 is an effective Rho-kinase inhibitor.
T24725	ROCK-IN-D3	ROCK inhibitor D3,ROCK-inhibitor-D3
	ROCK-IN-D3 is an effective and selective inhibitor of ROCK.
T4095	ZINC00881524	ROCK inhibitor	ROCK
	ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.		ROCK
T6867	Belumosudil	KD025,Rezurock,ROCK inhibitor,SLx-2119	ROCK
	Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).		ROCK
T63637	ROCK-IN-4
	ROCK-IN-4 is a potent inhibitor of ROCK and maintains NO release capacity.ROCK-IN-4 reversibly depolymerizes F-actin and blocks mitochondrial respiration in human trabecular meshwork (HTM) cells.ROCK-IN-4 can be used to ...
T79833	ROCK-IN-9		ROCK
	ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM. It demonstrates favorable pharmacokinetic properties in mice, achieving high in vivo exposure and oral bioavailab...		ROCK
T79080	ROCK-IN-7		ROCK
	ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].		ROCK
T79809	ROCK-IN-8		ROCK
	ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research, demonstrating an IC50 value below 100 nM [1].		ROCK
T79077	ROCK-IN-6		ROCK
	ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1].		ROCK
T70937	ROCK-IN-(R)14f
	ROCK-IN-(R)14f is a potent ROCK inhibitor.
T79905	Akt/ROCK-IN-1		ROCK
	Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 nM and 1.47 nM, respectively. It possesses antitumor efficacy against neuroblastoma [1].		ROCK
T12747	ROCK2-IN-2		ROCK
	ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).		ROCK
T2011	RKI1313	RKI 1313,RKI-1313	ROCK
	RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion.		ROCK
T2155	Thiazovivin		ROCK
	Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.		ROCK