Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 50.00 | |
200 mg | In stock | $ 79.00 | |
500 mg | In stock | $ 158.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities. |
In vitro | In diabetic nephropathy-afflicted db/db mice, Rhein effectively ameliorates diabetic renal lesions and mitigates hyperlipidemia by reducing plasma cholesterol (Chol), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), ApoE, and renal tissue transforming growth factor-β1 (TGF-β1). |
In vivo | In chondrocytes, Rhein (35 µM) effectively inhibits the synthesis of IL-1β in human osteoarthritis synovium and exerts effects in cartilage by reducing the amount of IL-1R and inhibiting the production of NO induced by IL-1β. Additionally, Rhein is capable of inducing apoptosis in acute promyelocytic leukemia cells (HL-60). |
Source |
Synonyms | Rheinic Acid, Monorhein, NSC 38629, Rheic Acid, Rhubarb yellow |
Molecular Weight | 284.22 |
Formula | C15H8O6 |
CAS No. | 478-43-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.45 mg/mL (19.19 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Rhein 478-43-3 Autophagy Immunology/Inflammation Metabolism Microbiology/Virology NF-Κb Antibacterial Reactive Oxygen Species Rheinic Acid Bacterial Inhibitor Monorhein NSC 38629 NSC-38629 Rheic Acid Rhubarb yellow inhibit NSC38629 inhibitor