Powder: -20°C for 3 years | In solvent: -80°C for 2 years
Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl Angiotensin-converting Enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril erbumine is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 52.00 | |
200 mg | In stock | $ 78.00 |
Description | Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril erbumine is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue. |
Targets&IC50 | ACE:1.05 nM |
Synonyms | S9490-3, Perindopril tert-butylamine salt |
Molecular Weight | 441.61 |
Formula | C23H43N3O5 |
CAS No. | 107133-36-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
H2O: 50 mg/mL (113.22 mM)
DMSO: 10 mg/mL (22.64 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Perindopril erbumine 107133-36-8 Apoptosis Endocrinology/Hormones Immunology/Inflammation RAAS MRP S9490-3 S 9490 inhibit Perindopril tert-butylamine Perindopril S-9490 Inhibitor Angiotensin-converting Enzyme (ACE) Perindopril tert-butylamine salt S9490 inhibitor