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TargetMol | Compound Library

Anti-Cancer Clinical Compound Library

Catalog No. L2120

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy,however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 2760 anti-cancer compounds currently in clinical trial phases based on published literatures and database to form this collection that can be used for high throughput screening and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2120

Anti-Cancer Clinical Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 2760 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers;
  • Effective tool for cancer research and drug repurposing screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc., in lung cancer, breast cancer, leukemia, lymphoma, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Apoptosis
Autophagy
Endogenous Metabolite
5-HT Receptor
Antibacterial
Adrenergic Receptor
DNA/RNA Synthesis
Dopamine Receptor
Antibiotic
VEGFR
COX
Potassium Channel
Calcium Channel
Histamine Receptor
Sodium Channel
Parasite
EGFR
PI3K
ROS
CDK
Cytochromes P450
Reactive Oxygen Species
NF-κB
FLT
PDGFR
JAK
Glucocorticoid Receptor
HIV Protease
Topoisomerase
mTOR
FGFR
c-Kit
HDAC
Akt
c-Met/HGFR
Microtubule Associated
PPAR
Virus Protease
AChR
Ferroptosis
Prostaglandin Receptor
SARS-CoV
Src
Dehydrogenase
Nucleoside Antimetabolite/Analog
GABA Receptor
p38 MAPK
Antifungal
Mitophagy
Estrogen Receptor/ERR
Tyrosine Kinases
ERK
iGluR
Estrogen/progestogen Receptor
Adenosine Receptor
Caspase
Bcr-Abl
Interleukin
Androgen Receptor
Influenza Virus
Ras
GPCR
Raf
TNF
PARP
HSV
Epigenetic Reader Domain
HSP
Bcl-2 Family
Aurora Kinase
P-gp
Serotonin Transporter
PDE
TRP/TRPV Channel
MEK
MDM-2/p53
ALK
HBV
Opioid Receptor
Trk receptor
HIF/HIF Prolyl-Hydroxylase
HER
ATPase
RAAS
PKC
Mitochondrial Metabolism
STAT
c-RET
Norepinephrine
TLR
c-Fms
Histone Methyltransferase
HCV Protease
Phosphatase
NMDAR
AMPK
ROS Kinase
DNA Alkylator/Crosslinker
JNK
Wnt/beta-catenin
Endothelin Receptor
GSK-3
E1/E2/E3 Enzyme
MMP
Chk
TAM Receptor
FAK
Proton pump
LPL Receptor
Progesterone Receptor
Gamma-secretase
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Beta Amyloid
Retinoid Receptor
S1P Receptor
KRas
Guanylate cyclase
CXCR
GluR
IGF-1R
SGLT
Reverse Transcriptase
HIF
CFTR
p53
NO Synthase
Carbonic Anhydrase
DNA-PK
Antifolate
IL Receptor
TGF-beta/Smad
Nrf2
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Antioxidant
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ROCK
P2X Receptor
DNA Alkylation
Vasopressin Receptor
ATM/ATR
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S6 Kinase
Transferase
ADC Cytotoxin
IAP
Hedgehog/Smoothened
Lipoxygenase
PLK
HMG-CoA Reductase
DHFR
Integrin
P2Y Receptor
GNRH Receptor
IDO
CSF-1R
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Angiotensin-converting Enzyme (ACE)
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MAPK
Sirtuin
Ligand for E3 Ligase
Anti-infection
Kinesin
Monoamine Oxidase
BTK
Mdm2
Glutathione Peroxidase
MRP
Leukotriene Receptor
MAO
RIP kinase
Antifection
PAK
OX Receptor
Casein Kinase
IκB/IKK
Cannabinoid Receptor
DNA Methyltransferase
IRAK
Histone Demethylase
Serine Protease
Smo
DNA
Antiviral
Phospholipase
Hydroxylase
Neurokinin receptor
Sigma receptor
PROTACs
Reductase
PERK
Tie-2
Pim
FXR
Glucagon Receptor
CCR
Ephrin Receptor
PD-1/PD-L1
IKZF
NADPH
Serine/threonin kinase
PYK2
DPP-4
Bradykinin Receptor
Cholinesterase (ChE)
Xanthine Oxidase
Telomerase
STING
GPCR19
CRFR
RSV
GHSR
Tyrosinase
Thrombin
NOD-like Receptor (NLR)
Chloride channel
CRM1
YAP
IFNAR
Melatonin Receptor
c-Myc
CaSR
Cholecystokinin Receptor
Photosensitizer
NAMPT
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Aryl Hydrocarbon Receptor
ABC Transporter
Na-K-Cl cotransporter
Glucosidase
Monoamine Transporter
Fatty Acid Synthase
Neuropeptide Y Receptor
Somatostatin
glycosidase
CaMK
DUB
Wee1
PGE Synthase
Aminopeptidase
GST
Aromatase
Oxytocin Receptor
CGRP Receptor
NOD
AhR
NOS
ROR
LTR
Rho
IRE1
Annexin A
MT Receptor
KSP
ATP Citrate Lyase
OXPHOS
BCRP
Beta-Secretase
OAT
Survivin
Free radical scavengers
transporter
Decarboxylase
FKBP
ribosome
Melanocortin Receptor
PDK
Adenosine Deaminase
Cuproptosis
Gap Junction Protein
Discoidin Domain Receptor (DDR)
Protease-activated Receptor
MLK
Monocarboxylate transporter
NEDD8
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
Arginase
Cell wall
Necroptosis
TOPK
VDA
Galectin
Cysteine Protease
RANKL/RANK
UGT
LDL
GRK
DNA gyrase
Hexokinase
PROTAC Linker
HCN Channel
Thrombopoietin Receptor
Acyltransferase
Porcupine
CD73
Histone Acetyltransferase
PAI-1
LPA Receptor
PI4K
SGK
Complement System
p97
Thyroid hormone receptor(THR)
Advanced Glycation End Products
MicroRNA
NPC1L1
Hydrogenase
RAR/RXR
MALT
MyD88
Factor VIIa
DYRK
MIF
GTPase
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OCT
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Hck
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Liver X Receptor
LIM Kinase
Neurotensin Receptor
Glucokinase
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Myosin
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GlyT
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MNK
GluCls
ASK
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KLF
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FOXO
RXFP receptor
NADPH-oxidase
BMI-1
Imidazoline Receptor
Ferroportin
Vitamin
Drug-Linker Conjugates for ADC
PGC-1α

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