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TargetMol | Compound Library

Anti-Cancer Clinical Compound Library

Catalog No. L2120

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy,however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 2760 anti-cancer compounds currently in clinical trial phases based on published literatures and database to form this collection that can be used for high throughput screening and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2120

Anti-Cancer Clinical Compound Library

sizeIn stock

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 2760 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers;
  • Effective tool for cancer research and drug repurposing screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc., in lung cancer, breast cancer, leukemia, lymphoma, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

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Apoptosis
Autophagy
Endogenous Metabolite
5-HT Receptor
Antibacterial
Adrenergic Receptor
DNA/RNA Synthesis
Dopamine Receptor
Antibiotic
VEGFR
COX
Potassium Channel
Calcium Channel
Histamine Receptor
Sodium Channel
EGFR
Parasite
PI3K
ROS
CDK
Cytochromes P450
Reactive Oxygen Species
NF-κB
FLT
JAK
PDGFR
Glucocorticoid Receptor
HIV Protease
FGFR
Topoisomerase
c-Kit
mTOR
HDAC
Akt
Microtubule Associated
c-Met/HGFR
PPAR
Virus Protease
AChR
Ferroptosis
Prostaglandin Receptor
SARS-CoV
Src
p38 MAPK
Dehydrogenase
Nucleoside Antimetabolite/Analog
GABA Receptor
Mitophagy
Estrogen Receptor/ERR
Antifungal
ERK
Interleukin
Tyrosine Kinases
iGluR
Estrogen/progestogen Receptor
Bcr-Abl
Adenosine Receptor
Caspase
Androgen Receptor
Influenza Virus
Ras
Raf
GPCR
TNF
Epigenetic Reader Domain
PARP
HSP
HSV
Aurora Kinase
P-gp
Bcl-2 Family
PDE
Serotonin Transporter
TRP/TRPV Channel
MEK
ALK
MDM-2/p53
Opioid Receptor
HBV
HER
Trk receptor
HIF/HIF Prolyl-Hydroxylase
RAAS
c-RET
PKC
STAT
Mitochondrial Metabolism
Histone Methyltransferase
Norepinephrine
TLR
ATPase
c-Fms
HCV Protease
Phosphatase
Endothelin Receptor
AMPK
NMDAR
ROS Kinase
DNA Alkylator/Crosslinker
JNK
Wnt/beta-catenin
Drug Metabolite
FAK
GSK-3
TAM Receptor
Beta Amyloid
E1/E2/E3 Enzyme
MMP
Chk
LPL Receptor
Proton pump
Retinoid Receptor
Molecular Glues
Gamma-secretase
S1P Receptor
Progesterone Receptor
Kras
Guanylate cyclase
CXCR
p53
NO Synthase
TGF-beta/Smad
SGLT
GluR
IGF-1R
CFTR
Reverse Transcriptase
Antifolate
Nrf2
DNA-PK
Carbonic Anhydrase
IL Receptor
HIF
P2X Receptor
Proteasome
PKA
DNA Alkylation
ATM/ATR
ROCK
S6 Kinase
Antioxidant
Syk
Vasopressin Receptor
HMG-CoA Reductase
Hedgehog/Smoothened
Transferase
ADC Cytotoxin
IAP
PLK
GNRH Receptor
Lipoxygenase
Ligands for E3 Ligase
Indoleamine 2,3-Dioxygenase (IDO)
Kinesin
DHFR
Integrin
CSF-1R
IDO
Anti-infection
Monoamine Oxidase
Sirtuin
P2Y Receptor
Angiotensin-converting Enzyme (ACE)
MAPK
MAO
Isocitrate Dehydrogenase (IDH)
BTK
MRP
RIP kinase
Antifection
OX Receptor
Glutathione Peroxidase
Leukotriene Receptor
Cannabinoid Receptor
IκB/IKK
DNA Methyltransferase
Histone Demethylase
Casein Kinase
Mdm2
PAK
IRAK
Smo
Phospholipase
Neurokinin receptor
Antiviral
DNA
Hydroxylase
Sigma receptor
Serine Protease
FXR
Reductase
Tie-2
Pim
PROTACs
CCR
Glucagon Receptor
Ephrin Receptor
PD-1/PD-L1
IKZF
PYK2
Serine/threonin kinase
Bradykinin Receptor
Xanthine Oxidase
STING
Tyrosinase
IFNAR
NADPH
Telomerase
Thrombin
NOD-like Receptor (NLR)
PERK
Cholinesterase (ChE)
DPP-4
GPCR19
RSV
CRFR
GHSR
CRM1
Glutaminase
Fatty Acid Synthase
Somatostatin
Wee1
PGE Synthase
Chloride channel
Melatonin Receptor
Aryl Hydrocarbon Receptor
CGRP Receptor
Cholecystokinin Receptor
Glucosidase
YAP
Na-K-Cl cotransporter
Neuropeptide Y Receptor
CaMK
AhR
ABC Transporter
Monoamine Transporter
glycosidase
DUB
c-Myc
CaSR
Photosensitizer
NAMPT
GST
Aromatase
Oxytocin Receptor
NOD
BCRP
Survivin
Aminopeptidase
Cuproptosis
Discoidin Domain Receptor (DDR)
Protease-activated Receptor
IRE1
KSP
OXPHOS
Free radical scavengers
FKBP
MLK
Beta-Secretase
Decarboxylase
Adenosine Deaminase
Annexin A
MT Receptor
transporter
PDK
LTR
ATP Citrate Lyase
ribosome
ROR
OAT
Rho
Melanocortin Receptor
Gap Junction Protein
UGT
Thrombopoietin Receptor
p97
NOS
Monocarboxylate transporter
Cysteine Protease
LDL
DNA gyrase
TOPK
Acyltransferase
Necroptosis
RANKL/RANK
GRK
LPA Receptor
SGK
NEDD8
VDA
PROTAC Linker
Porcupine
CD73
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
Galectin
Hexokinase
PI4K
Complement System
Arginase
DYRK
HCN Channel
Histone Acetyltransferase
PAI-1
MIF
Neurotensin Receptor
GlyT
ASK
Methionine Adenosyltransferase (MAT)
Aquaporin
RAR/RXR
MALT
MyD88
Cadherin
Huntingtin
GluCls
Pyroptosis
RXFP receptor
NADPH-oxidase
Thyroid hormone receptor(THR)
NPC1L1
Kisspeptin
Myosin
Thioredoxin
Neprilysin
FOXO
Liposome
Advanced Glycation End Products
Cell wall
OCT
Hck
Stemness kinase
ACK1
Lipid
PSMA
BMI-1
Hydrogenase
Factor VIIa
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
E3 Ligase Ligand-Linker Conjugates
Hippo pathway
Imidazoline Receptor
MicroRNA
LIM Kinase
Glucokinase
PAFR
MTH1
HCAR
MNK
KLF
GTPase
Factor Xa
Liver X Receptor
MELK
Vitamin
Drug-Linker Conjugates for ADC
Ferroportin
PGC-1α

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