Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression.
Description | Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression. |
Targets&IC50 | GRK2:14 μM |
Cell Research | Paroxetine is dissolved in DMSO. Cell viability is determined by the tetrazolium salt 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay. BV2 and primary microglial cells are initially seeded into 96-well plates at a density of 1×104 cells/well and 5×104 cells/well, respectively. Following treatment, MTT (5 mg/mL in PBS) is added to each well and incubated at 37°C for four hours. The resulting formazan crystals are dissolved in dimethylsulfoxide (DMSO). The optical density is measured at 570 nm, and results are expressed as a percentage of surviving cells compared with the control. |
Synonyms | Paroxetine HCl, 盐酸帕罗西汀, BRL29060 hydrochloride, FG-7051, BRL29060A |
Molecular Weight | 365.83 |
Formula | C19H21ClFNO3 |
CAS No. | 78246-49-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: 10 mg/mL (27.33 mM)
Ethanol: 35 mg/mL (95.67 mM)
DMSO: 73 mg/mL (199.54 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Paroxetine hydrochloride 78246-49-8 G蛋白偶联受体 神经科学 自噬 5-HT Receptor AChR Autophagy GRK Serotonin Transporter BRL29060A BRL 29060 inhibit Paroxetine SLC6A4 BRL29060 FG-7051 Inhibitor SERT BRL-29060 5-HTT BRL29060 hydrochloride Paroxetine HCl inhibitor