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Olodaterol hydrochloride

Catalog No. T5159 CAS 869477-96-3

Synonyms: BI-1744 HCl, BI 1744 hydrochloride

Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist (EC50s: 97.7 nM for the human β2-adrenoceptor) that exerts its pharmacological effect by binding and activating β2-adrenergic receptors.

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Olodaterol hydrochloride Chemical Structure

Olodaterol hydrochloride, CAS 869477-96-3

Pack Size	Availability	Price/USD
1 mg	In stock	$ 56.00
2 mg	In stock	$ 79.00
5 mg	In stock	$ 122.00
10 mg	In stock	$ 198.00
25 mg	In stock	$ 369.00
50 mg	In stock	$ 549.00
100 mg	In stock	$ 788.00

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Purity: 99.58%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist (EC50s: 97.7 nM for the human β2-adrenoceptor) that exerts its pharmacological effect by binding and activating β2-adrenergic receptors.
Targets&IC50	β2-adrenoceptor (human):97.7 nM(EC50)

Synonyms	BI-1744 HCl, BI 1744 hydrochloride
Molecular Weight	422.9
Formula	C21H27ClN2O5
CAS No.	869477-96-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL

H2O: 15 mg/mL

References and Literature

1. Bouyssou T, et al. Discovery of olodaterol, a novel inhaled beta2-adrenoceptor agonist with a 24 h bronchodilatory efficacy. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4. 2. Herrmann F E, et al. Olodaterol shows anti‐fibrotic efficacy in in vitro and in vivo models of pulmonary fibrosis. Br J Pharmacol, 2017, 174(21):3848. 3. Bouyssou T, et al. Pharmacological characterization of olodaterol, a novel inhaled beta2-adrenoceptor agonist exerting a 24-hour-long duration of action in preclinical models. J Pharmacol Exp Ther. 2010 Jul;334(1):53-62.

Citations

1. Guo Q, He B, Zhong Y, et al.A method for structure determination of GPCRs in various states.Nature Chemical Biology.2023: 1-9.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library GPCR Compound Library Membrane Protein-targeted Compound Library Adrenergic Receptor-Targeted Compound Library Approved Drug Library Neurotransmitter Receptor Compound Library Anti-Alzheimer's Disease Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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