Powder: -20°C for 3 years | In solvent: -80°C for 1 year
J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 42.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 158.00 | |
50 mg | In stock | $ 242.00 | |
100 mg | In stock | $ 411.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 77.00 |
Description | J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death |
Targets&IC50 | Sulfiredoxin:8.1 μM |
Synonyms | J-14 |
Molecular Weight | 517.04 |
Formula | C28H25ClN4O2S |
CAS No. | 1043854-13-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 260 mg/mL (502.86 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
J14 1043854-13-2 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species cancer inhibit damage Sulfiredoxin cytotoxicity death adenocarcinoma Inhibitor lung J-14 mitochondrial cells J 14 inhibitor