Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 80.00 | |
20 mg | In stock | $ 120.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects. |
Source |
Molecular Weight | 360.31 |
Formula | C18H16O8 |
CAS No. | 548-76-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL(180.4 mM)
You can also refer to dose conversion for different animals. More
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Irigenin 548-76-5 Cytoskeletal Signaling NF-Κb NF-κB Integrin inhibit cancer lung transition metastasis apoptosis Epithelial-Mesenchymal C-C TRAIL EDA gastric loop carcinoma Inhibitor inhibitor