store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IMT1B (LDC203974) is an orally administered, specific noncompetitive allosteric inhibitor of the mitochondrial RNA polymerase (POLRMT), effectively suppressing mitochondrial DNA (mtDNA) expression. This action confers it with anti-tumor properties.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
5 mg | In stock | $ 328.00 | |
10 mg | In stock | $ 563.00 | |
25 mg | In stock | $ 890.00 | |
50 mg | In stock | $ 1,230.00 | |
100 mg | In stock | $ 1,670.00 | |
500 mg | In stock | $ 3,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 343.00 |
Description | IMT1B (LDC203974) is an orally administered, specific noncompetitive allosteric inhibitor of the mitochondrial RNA polymerase (POLRMT), effectively suppressing mitochondrial DNA (mtDNA) expression. This action confers it with anti-tumor properties. |
Synonyms | 3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-, LDC203974 |
Molecular Weight | 473.88 |
Formula | C24H21ClFNO6 |
CAS No. | 2304621-06-3 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (527.56 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
IMT1B 2304621-06-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair Others DNA/RNA Synthesis Inhibitor inhibit POLRMT oxidative IMT-1B human LDC 203974 anti-tumour mtDNA 3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)- phosphorylation OXPHOS RNA mitochondrial LDC203974 DNA polymerase LDC-203974 inhibitor