keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 55.00 | |
5 mg | In stock | $ 163.00 | |
10 mg | In stock | $ 263.00 | |
25 mg | In stock | $ 447.00 | |
50 mg | In stock | $ 646.00 | |
100 mg | In stock | $ 888.00 |
Description | Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. |
Targets&IC50 | PACE4:580 nM (KI), PC1:13.2 mM (ki), Furin:106 nM (KI) |
In vivo | The small stable furin inhibitor hexa-D-arginine amide effectively blocks PEA-induced cell lysis and is itself noncytotoxic.?Administration of hexa-D-arginine to PEA-treated mice significantly improves their survival rate and also decreases circulating levels of tumor necrosis factor alpha[1]. |
Molecular Weight | 954.14 |
Formula | C36H75N25O6 |
CAS No. | 673202-67-0 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 50mg/L (52.40mM)
DMSO: 20.96mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Hexa-D-arginine 673202-67-0 Others inhibit furin Furin Inhibitor II TNF-α PACE4 noncytotoxic PC1 anthrax PEA HexaDarginine Hexa D arginine exotoxins Inhibitor inhibitor