furin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7495	Hexa-D-arginine		Others
	Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.		Others
TP1160	Hexa-D-arginine TFA	Furin Inhibitor II TFA
	Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).
T9964	BOS-318		Others
	BOS-318 is a Furin inhibitor with slowly dissociating, highly selective, and cell-pemeable characteristcs.		Others
T40686	Tiazofurin	NSC 286193,Riboxamide	Dehydrogenase
	Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) in...		Dehydrogenase
T70221	Dibefurin
	Dibefurin is a metabolite that inhibits the activity of calcineurin, a calcium/calmodulin-dependent protein phosphatase involved in the activation of T lymphocytes.
T16690	Pyrazofurin		Others
	Pyrazofurin is a pyrimidine nucleoside analogue, inhibits cell proliferation and DNA synthesis in cells by inhibiting UMP synthase. Pyrazofurin is a sensitive orotate-phosphoribosyltransferase inhibitor (IC50s between 0....		Others
T30002	Ammifurin
	Ammifurin is a Furocoumarin mixture used in treatment of vitiligo.
T28744	Selenazofurin	BRN 4198668,CI-935,CI 935,CI935
	Selenazofurin is an antiviral compound. Selenazofurin inhibits the cytopathic effect and yield of influenza A/NWS/33 virus with 50% effective dose ranges of 0.7 to 1.4 micrograms/ml.
T41178	SSM 3 trifluoroacetate
	SSM 3 trifluoroacetate is a potent furin inhibitor (EC50= 54 nM). Blocks furin-dependent cell surface processing of anthrax protective antigen-83in vitro.
T68339	SSM3 TFA
	SSM3 TFA is a potent furin inhibitor, blocking furin-dependent cell surface processing of anthrax protective antigen-83 in vitro..
T78121	SSM3 tetraTFA hydrate		Others
	SSM3 tetraTFA hydrate is a potent synthetic inhibitor of furin, exhibiting an EC50 of 54 nM and a Ki of 12 nM. It effectively inhibits the furin-dependent cell surface processing of anthrax protective antigen-83 in vitro...		Others
T76607	Boc-Arg-Val-Arg-Arg-AMC hydrochloride
	Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate efficiently cleaved by the enzyme furin.
T69640	MI-1851
	MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.
TP2038	Decanoyl-RVKR-CMK
	Subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin). Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion ...
T82592	DEC-RVRK-CMK	Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
	Decanoyl-Arg-Val-Arg-Lys-chloromethylketone (DEC-RVRK-CMK) is a small, synthetic, irreversible cell-permeable competitive inhibitor of furin that exhibits strong antiviral activity against Zika virus (ZIKV) and Japanese ...
T78224	Histatin-3
	Histatin-3, a 32-amino-acid peptide, exhibits potent antimicrobial activities and serves as a substrate for proprotein convertase 1 (PC1), where it is primarily cleaved at a site carboxy-terminal to Arg25 (HRGYR↓SN). Add...