5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7495 | Hexa-D-arginine | Others | |
Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. | |||
T4217 | INF39 | NOD-like Receptor (NLR) , NOD | |
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor. | |||
T72399 | LIMK1 inhibitor BMS-4 | ||
LIMK1 inhibitor BMS-4 is a compound targeting LIM Kinase (LIMK) 1/2, specifically inhibiting the phosphorylation of its substrate, cofilin, but it remains noncytotoxic on A549 cells. | |||
T9811 | JAK3-IN-11 | ||
JAK3-IN-11 (Compound 12) exhibits potent, noncytotoxic, irreversible, orally active JAK3 inhibitory activity (IC50 = 1.7 nM) with an excellent selectivity profile (>588-fold compared to other JAK isoforms), covalently bi... | |||
T71966 | PD-128763 | ||
PD-128763 is a selective inhibitor of poly(ADP-ribose) polymerase. PD-128763 has an IC50 value against the purified enzyme approximately 50X lower than 3-aminobenzamide (3-AB), a widely used specific inhibitor of the enz... |