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Glycocholic acid

Catalog No. T2831 CAS 475-31-0

Synonyms: Glycocholate, cholylglycine

Glycocholic acid (Glycocholate) is a bile acid with anticancer activity. Glycocholic acid targets against pump resistance-related and non-pump resistance-related pathways.

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Glycocholic acid, CAS 475-31-0

Pack Size	Availability	Price/USD	Quantity
500 mg	In stock	$ 50.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.84%

Purity: 99.71%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Glycocholic acid (Glycocholate) is a bile acid with anticancer activity. Glycocholic acid targets against pump resistance-related and non-pump resistance-related pathways.

Kinase Assay

Topoisomerase I-DNA interaction: Annealed 25-mer duplex of oligonucleotide-1 and oligonicleotide-2 is incubated with 25 or 50 units of rat liver topoisomerase I at 8 °C for 15 min in the presence or absence of betulinic acid in binding buffer. After incubation the reaction mixtures are electrophoresed in 7% non-denaturing polyacrylamide gel at 4 °C in 0.167 × TBE buffer and DNA bands are stained with ethidium bromid

Synonyms	Glycocholate, cholylglycine
Molecular Weight	465.62
Formula	C26H43NO6
CAS No.	475-31-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 84 mg/mL(180.4 mM)

References and Literature

1. Zhang A, et al. Clin Chim Acta. 2013 Mar 15;418:86-90.

Citations

1. Qiu Q, Guo G, Guo X, et al.P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.Biomedicines.2023, 11(3): 882.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Human Endogenous Metabolite Library Anti-Cancer Drug Library Microbial Natural Product Library Anti-Cancer Clinical Compound Library Drug Repurposing Compound Library Natural Product Library Bioactive Compound Library Anti-Tumor Natural Product Library Pediatric Drug Library

Related Products

Related compounds with same targets

Sucralose Copper tripeptide NADH disodium salt Rebaudioside C 2'-Deoxyadenosine monohydrate γ-L-Glutamyl-L-alanine 3,3-Dimethylglutaric acid 7-Methylguanosine

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Glycocholic acid 475-31-0 Metabolism Others Endogenous Metabolite Glycocholate inhibit cholylglycine Inhibitor inhibitor

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