Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.46).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 188.00 | |
50 mg | In stock | $ 283.00 | |
100 mg | In stock | $ 422.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.46). |
In vitro | Estrogen receptor modulator 1 (100 nM; 9 days) obviously inhibits the growth of MCF-7:5C cell. It also causes apoptosis in these cells 6 days. Estrogen receptor modulator 1 (100 nM; 10 days) inhibits T47D:A18/PKCα and T47D:A18-TAM1 colony formation [2]. |
In vivo | Estrogen receptor modulator 1 (1.5 mg/animal; p.o. ; daily for 2 weeks) causes regression of T47D:A18/PKCα tumors[2]. |
Molecular Weight | 242.29 |
Formula | C14H10O2S |
CAS No. | 63676-22-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (206.36 mM)
You can also refer to dose conversion for different animals. More
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Estrogen receptor modulator 1 63676-22-2 Endocrinology/Hormones Estrogen Receptor/ERR MCF-7:5C cancer selective Estrogen receptor modulator1 breast Estrogen receptor modulator-1 cells tumor athymic mice inhibit Inhibitor inhibitor