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Home > PI3K/Akt/mTOR signaling > PDK > BX912

BX912

Catalog No. T1837    CAS 702674-56-4   

BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC etc.

Pack Size Availability Price/USD Quantity
2 mg In stock 81.00
5 mg In stock 134.00
10 mg In stock 242.00
25 mg In stock 435.00
100 mg Inquiry 782.00
1 mL * 10 mM (in DMSO) In stock 136.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC etc.

Receptor:

CDK2/CyclinE; Chk1; PDK1; PKA; VEGFR2 (KDR);

Chemical Information:
Molecular Weight 471.35
Formula C20H23BrN8O
CAS Number 702674-56-4
Solubility

DMSO: 87 mg/mL (184.6 mM)

Ethanol: 87 mg/mL (184.6 mM)

Water: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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