T1266 |
Terfenadine
|
50679-08-8
|
99.36%
|
|
Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist...
|
T2959 |
Ginsenoside Rh2
|
78214-33-2
|
99.20%
|
|
Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.
|
TN1891 |
Lupiwighteone
|
104691-86-3
|
99.20%
|
|
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.
|
T6826 |
Emricasan
|
254750-02-2
|
99.11%
|
|
Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the ...
|
T4241 |
Rubiadin
|
117-02-2
|
99.1%
|
|
Rubiadin (1,3-Dihydroxy-2-Methylanthracene-9,10-Dione) possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydro...
|
T75319 |
Taurodeoxycholic acid
|
516-50-7
|
99.09%
|
|
Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes an...
|
T70038 |
MJN68390
|
1956368-39-0
|
99.06%
|
|
MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.
|
T5S2283 |
Sesamolin
|
526-07-8
|
98.89%
|
|
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 ac...
|
TJA2398 |
Taurodeoxycholic acid sodium hydrate
|
110026-03-4
|
98.87%
|
|
Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.
|
TN1675 |
Gardenin B
|
2798-20-1
|
98.71%
|
|
Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .
|
T9118 |
KEA1-97
|
2138882-71-8
|
98.7%
|
|
Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspa...
|
TQ0146 |
Ac-DEVD-CHO
|
169332-60-9
|
98.69%
|
|
Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM).Ac-DEVD-CHO has an inhibitory effect in SLNT-induced apoptosis.
|
T1772 |
MDK83190
|
79183-19-0
|
98.67%
|
|
MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .
|
T7020 |
Z-VAD-FMK
|
161401-82-7
|
98.63%
|
|
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases with irreversible properties. Z-VAD-FMK binds to activated caspases, thereby inhibitin...
|
T21936 |
M50054
|
54135-60-3
|
98.62%
|
|
Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.
|
T77579 |
JC2-11
|
937820-89-8
|
98.6%
|
|
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical ...
|
TQ0146L |
Ac-DEVD-CHO acetate
|
TQ0146L
|
98.54%
|
|
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.
|
T27242 |
EF24
|
342808-40-6
|
98.47%
|
|
EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of M...
|
T5S2358 |
Dehydrocorydaline
|
30045-16-0
|
98.36%
|
|
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stim...
|
T0859 |
Fenbufen
|
36330-85-5
|
98.35%
|
|
Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It ...
|