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AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T16881 SIB-1553A hydrochloride 191611-89-9 99.52%
SIB-1553A hydrochloride
SIB-1553A hydrochloride is an orally available, selective nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand.SIB-1553A hydrochloride ...
T17300 (-)-(S)-B-973B 2244989-34-0 99.52%
(-)-(S)-B-973B
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
T22371 Mivacurium dichloride 106861-44-3 99.52%
Mivacurium dichloride
Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skelet...
T0851 Pregnenolone 145-13-1 99.5%
Pregnenolone
Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
T5S0802 Palmatine 3486-67-7 99.49%
Palmatine
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palma...
T9353 OXOMEMAZINE 3689-50-7 99.49%
OXOMEMAZINE
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M...
T23145 PHA 543613 478149-53-0 99.48%
PHA 543613
PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.
TN1305 Ethoxysanguinarine 28342-31-6 99.48%
Ethoxysanguinarine
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory acti...
T1484 Perindoprilat 95153-31-4 99.48%
Perindoprilat
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
T1231 Pilocarpine nitrate 148-72-1 99.48%
Pilocarpine nitrate
Pilocarpine nitrate (Pilagan) is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glauco...
T1682 Methacholine Chloride 62-51-1 99.47%
Methacholine Chloride
Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hy...
T8196 Arborine 6873-15-0 99.46%
Arborine
Arborine (Arborin) is a larval growth inhibitor from glycoslnis pentaphylla.
TN1643 Ferulamide 61012-31-5 99.45%
Ferulamide
Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.
T23297 (S)-(+)-Dimethindene maleate 136152-65-3 99.43%
(S)-(+)-Dimethindene maleate
(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1, M3, and M...
T17238 VU0152100 409351-28-6 99.43%
VU0152100
VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).
T0862 Diphenidol hydrochloride 3254-89-5 99.42%
Diphenidol hydrochloride
Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.
T9542 NS3861 216853-59-7 99.40%
NS3861
NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and bind with high affinity to heteromeric α3β4 and α4β2 nAChRs. NS3861 displays the β-subunit...
T0236 Azatadine dimaleate 3978-86-7 99.4%
Azatadine dimaleate
Azatadine dimaleate (SCH10649) is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).
TN3466 Atherosperminine 5531-98-6 99.4%
Atherosperminine
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong ant...
T1668 Vinblastine sulfate 143-67-9 99.38%
Vinblastine sulfate
Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
SIB-1553A hydrochloride
T16881
SIB-1553A hydrochloride is an orally available, selective nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand.SIB-1553A hydrochloride ...
(-)-(S)-B-973B
T17300
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
Mivacurium dichloride
T22371
Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skelet...
Pregnenolone
T0851
Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
Palmatine
T5S0802
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palma...
OXOMEMAZINE
T9353
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M...
PHA 543613
T23145
PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.
Ethoxysanguinarine
TN1305
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory acti...
Perindoprilat
T1484
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
Pilocarpine nitrate
T1231
Pilocarpine nitrate (Pilagan) is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glauco...
Methacholine Chloride
T1682
Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hy...
Arborine
T8196
Arborine (Arborin) is a larval growth inhibitor from glycoslnis pentaphylla.
Ferulamide
TN1643
Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.
(S)-(+)-Dimethindene maleate
T23297
(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1, M3, and M...
VU0152100
T17238
VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).
Diphenidol hydrochloride
T0862
Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.
NS3861
T9542
NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and bind with high affinity to heteromeric α3β4 and α4β2 nAChRs. NS3861 displays the β-subunit...
Azatadine dimaleate
T0236
Azatadine dimaleate (SCH10649) is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).
Atherosperminine
TN3466
Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong ant...
Vinblastine sulfate
T1668
Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
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TargetMol