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Methacholine Chloride

Catalog No. T1682   CAS 62-51-1
Synonyms: Mecholyl chloride, Acetyl-β-methylcholine chloride

Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma.

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Methacholine Chloride Chemical Structure
Methacholine Chloride, CAS 62-51-1
Pack Size Availability Price/USD Quantity
100 mg In stock $ 59.00
200 mg In stock $ 87.00
1 mL * 10 mM (in DMSO) In stock $ 47.00
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Purity: 99.74%
Purity: 99.47%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma.
Synonyms Mecholyl chloride, Acetyl-β-methylcholine chloride
Molecular Weight 195.69
Formula C8H18ClNO2
CAS No. 62-51-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (255.51 mM)

TargetMolReferences and Literature

1. Liu PS, et al. Eur J Pharmacol. 2011 Jan 10;650(1):34-40.

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library Membrane Protein-targeted Compound Library Anti-Neurodegenerative Disease Compound Library NO PAINS Compound Library ReFRAME Related Library Pediatric Drug Library Approved Drug Library Anti-Parkinson's Disease Compound Library Drug-Fragment Library Bioactive Compounds Library Max

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Keywords

Methacholine Chloride 62-51-1 Neuroscience AChR Acetyl-b-methylcholine Chloride Muscarinic acetylcholine receptor mAChR airway hyperresponsiveness Methacholine Inhibitor asthma-like Mecholyl chloride bronchoconstriction Acetyl-beta-methylcholine Chloride Acetyl-β-methylcholine Chloride Mecholyl Chloride Acetyl-β-methylcholine chloride inhibit inhibitor

 

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