vasopressin-v2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6288	Mozavaptan	OPC31260l,OPC-31260	Vasopressin Receptor
	Mozavaptan (OPC-31260) is a competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.		Vasopressin Receptor
T64174	Vasopressin V2 receptor antagonist 1
	Vasopressin V2 receptor antagonist 1 (Compound 4g) is a vasopressin V2receptor (V2R) antagonist (Ki: 3.8 nM). dominant polycystic kidney disease (ADPKD).
T7303	LIXIVAPTAN	VPA-985,WAY-VPA 985	Vasopressin Receptor
	Lixivaptan (VPA-985) is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM)		Vasopressin Receptor
T6453	Conivaptan hydrochloride	Vaprisol,Conivaptan HCl,YM 087	Vasopressin Receptor
	Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in the therapy of hypervolemic hyponatremia and euvolemic.		Vasopressin Receptor
T15273	Fedovapagon	VA483,A106483	Vasopressin Receptor
	Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. Fedovapagon can be used to study overactive bladder, nocturia...		Vasopressin Receptor
T5144	Desmopressin acetate (16679-58-6 free base)	Desmopressin acetate,DDAVP	Vasopressin Receptor
	Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyur...		Vasopressin Receptor
T2326	Tolvaptan	OPC-41061	Vasopressin Receptor , Autophagy
	Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia.		Vasopressin Receptor , Autophagy
TP2082L	D[Cha4]-AVP acetate(500170-27-4 free base)		Vasopressin Receptor
	d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secre...		Vasopressin Receptor
T28629	RWJ 676070	RWJ676070,RWJ-676070
	RWJ 676070 is an antagonist of vasopressin V1A/V2 receptor.
T29178	YM 471	YM-471,YM471
	YM 471 is a non-peptide arginine vasopressin (AVP) V1A and V2 receptor antagonist with oral activity.
T24759	Satavaptan fumarate	SR-121463A,SR 121463 A,SR-121463 A,SR121463A
	Satavaptan fumarate is a selective antagonist of the non-peptide vasopressin V2 receptor.
T24370	L-368899 free base	L 368899,L 368,899,L368,899,L-368899,L368899,L-368,899
	L-368899 is a non-peptide and orally active antagonist of oxytocin receptor (IC50: 8.9 nM). It displays 40-fold selectivity over vasopressin V1a and V2 receptors (IC50: 370 and 570 nM respectively).
T27965	M-0002	RWJ-351647,SPD556,SPD-556,M0002,RWJ351647
	M-0002, a vasopressin V2 receptor antagonist, is used potentially for the treatment of ascites.
T28664	Satavaptan	SR121463,SR 121463,SR-121463
	Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.
T17251	VNA-932	WAY-VNA 932	Others
	VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay).		Others
T62906	Lazuvapagon
	Lazuvapagon is a vasopressin V2 receptor agonist that can be used to study enuresis.
TP2082	D[Cha4]-AVP
	Potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligi...
T16934	SRX246		Others
	SRX246 has no interaction at V1b and V2 receptors. SRX246 shows negligible binding at 64 other receptors classes, including 35 G-proteincoupled receptors. SRX246 is a potent and CNS-penetrant vasopressin 1a (V1a) recepto...		Others
TP1927	D[Leu4,Lys8]-VP
	Selective vasopressin V1B receptor agonist (Ki values are 0.16, 64, 100 and 3800 nM for V1B, oxytocin, V2 and V1A receptors respectively). Displays weak antidiuretic, vasopressor and in vitro oxytocic activities.
T75933	D[Cha4]-AVP TFA
	d[Cha4]-AVP TFA is a potent and selective agonist for the vasopressin (AVP) V1b receptor, displaying a high affinity with a K i of 1.2 nM. It exhibits greater selectivity for the V1b receptor over the V1a receptor, V2 re...