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Desmopressin acetate (16679-58-6 free base)

Catalog No. T5144 CAS 62288-83-9

Synonyms: DDAVP, Desmopressin acetate

Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. <a href="/target/Vasopressin_Receptor" style="display: inline; color: #c13a36">Vasopressin Receptor</a> The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

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Desmopressin acetate (16679-58-6 free base), CAS 62288-83-9

Pack Size	Availability	Price/USD
2 mg	In stock	$ 62.00
5 mg	In stock	$ 99.00
10 mg	In stock	$ 148.00
25 mg	In stock	$ 252.00
50 mg	In stock	$ 379.00
100 mg	In stock	$ 567.00

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Purity: 100%

Biological Description

Chemical Properties

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Description

Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

Synonyms	DDAVP, Desmopressin acetate
Molecular Weight	1129.28
Formula	C48H68N14O14S2
CAS No.	62288-83-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 50 mg/mL

DMSO: 10 mM

Ethanol: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kaufmann JE, et al. Desmopressin (DDAVP) induces NO production in human endothelial cells via V2 receptor- and cAMP-mediated signaling. J Thromb Haemost. 2003 Apr;1(4):821-8. 2. Tsukamoto I. Recent patenting activities in the discovery and development of vasopressin V2 receptor agonists. Expert Opin Ther Pat. 2012 Jun;22(6):579-86.

Citations

1. Wang S Q, Li C L, Xu J Q, et al. The Effect of Endolymphatic Hydrops and Mannitol Dehydration Treatment on Guinea Pigs. Frontiers in Cellular Neuroscience. 2022, 16

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Clinical Compound Library Clinical Compound Library Drug Repurposing Compound Library Bioactive Compounds Library Max Orally Active Compound Library FDA-Approved & Pharmacopeia Drug Library FDA-Approved Drug Library Bioactive Compound Library Peptide Compound Library NO PAINS Compound Library

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Keywords

Desmopressin acetate (16679-58-6 free base) 62288-83-9 GPCR/G Protein Vasopressin Receptor Desmopressin acetate (16679 58 6 free base) DDAVP Desmopressin acetate Desmopressin acetate (16679586 free base) Inhibitor inhibitor inhibit

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