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Search Results for " transferrin "

18

Compounds

Cat No. Product Name Synonyms Targets
TP2298L transferrin fragment acetate Others
Transferrin fragment acetate is the principal ironbinding protein in animal serum and is analogous in its iron-binding site and properties to lactoferrin1.
TP2298 transferrin fragment Others
Transferrin is the principal iron-binding protein in animal serum and is analogous in its iron-binding site and properties to lactoferrin1. Human transferrin is a single-chain glycoprotein of molecular weight near 80,000...
T13692 Ferric maltol Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate Others
Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) is a ferric, non-salt-based oral iron formulation demonstrating improved tolerance in patients with previous intolerance to other iron formulations.
T78022 Transferrins
Transferrin, a blood-plasma glycoprotein, serves as a specific ligand for the transferrin receptor and facilitates the binding and transport of iron [1] [2] [3].
T80100 Ovotransferrin (328-332) Angiotensin-converting Enzyme (ACE)
Ovotransferrin (328-332), with an IC50 of 20 μM, exhibits protective activity against hypertension by inhibiting the Angiotensin-Converting Enzyme (ACE) and also displays anti-Cholinesterase (ChE) activity, suggesting a ...
T80257 Lactoferricin H, Lactotransferrin (37-61), human
Lactoferricin H, Lactotransferrin (37-61), human, is a bioactive peptide with antimicrobial properties, derived from the amino acid residues 37-61 of human lactotransferrin.
T40428L TfR-T12 acetate TfR-T12 acetate (344618-30-0 Free base) Others
TfR-T12 acetate is a peptide binding to the transferrin receptor (TfR) and is subsequently internalized into TfR-expressing cells.
T34973 Tyrphostin 8 4-Hydroxybenzylidenemalononitrile EGFR , GTPase
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances ...
T4058 R-IMPP Others , Serine/threonin kinase
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
T80622 Trontinemab
Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC). It is utilized in research on Alzheimer's disease (AD) [1] [2].
T64368 ES9-17 Others
ES9-17, an analog of ES9 (endosidin9), is an inhibitor of clathrin-mediated endocytosis (CME). ES9-17 inhibits the uptake of FM4-64 and transferrin. ES9-17 inhibits root growth of Arabidopsis seedings.
T37020 Endosidin-2 ES2,Endosidin 2
Endosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1).Endosidin-2 disrupts pro...
T26639 Ap44mSe
Ap44mSe is a potent and selective antitumor agent. Ap44mSe effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis ...
T40428 TfR-T12 TfR-T12
TfR-T12 is a transferrin receptor (TfR) binding peptide that can penetrate the blood-brain barrier (BBB), exhibiting a high binding affinity within the nanomolar (nM) range.
T15135L Direct Black 38 free acid NSC8679,Ferristatin II Others
Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.
T81573 Pabinafusp alfa JR-141
Pabinafusp alfa (JR-141), a transferrin receptor-targeting antibody fusing Iduronate 2-sulfatase with an anti-human transferrin receptor antibody, penetrates the blood-brain barrier and inhibits heparan sulfate (HS) accu...
T78374 TfR-T12 TFA
TfR-T12 TFA, a transferrin receptor (TfR)-binding peptide capable of crossing the blood-brain barrier (BBB), exhibits nanomolar (nM) binding affinity [1] [2].
T78014 HAIYPRH hydrochloride
HAIYPRH hydrochloride is a targeting ligand that specifically binds to the transferrin receptor (TfR) and facilitates the transport of nanocarriers across the blood-brain barrier [1].
TargetMol