20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1604L | Thioredoxin reductase peptide acetate | Thioredoxin reductase peptide acetate(950890-23-0 free base) | Others |
Thioredoxin reductase peptide acetate corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active... | |||
TP1604 | Thioredoxin reductase peptide | ||
Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfi... | |||
TP1375 | Thioredoxin reductase peptide TFA | ||
Thioredoxin reductase peptide TFA corresponds to residues 53-67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.. | |||
T13230 | TXNIP-IN-1 | Others | |
TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease. | |||
T5481 | TRi-1 | Others | |
TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy | |||
T20168 | Aurothiomalate sodium | Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate | Others , PKC |
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ... | |||
T9118 | KEA1-97 | Apoptosis , Others , Caspase | |
Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity ... | |||
T4414 | Eprenetapopt | APR-246,PRIMA-1Met | Apoptosis , Others , Ferroptosis , p53 , Autophagy |
Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of c... | |||
T5372 | L-SelenoMethionine | L-(+)-Selenomethionine | Apoptosis , Amino Acids and Derivatives , Endogenous Metabolite |
L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase. | |||
T60446 | LCS3 | Apoptosis , Glutathione reductase | |
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, in... | |||
T2283 | PX-12 | IV-2,PX12 | Thioredoxin |
PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor gr... | |||
T29018 | TrxR inhibitor D9 | D9,TrxR-IN-D9 | |
TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR). | |||
T23166 | PMX 464 | Others | |
inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system | |||
T24593 | PAO-PDT | PAO PDT | |
PAO-PDT is a highly selective thioredoxin reductase inhibitor. | |||
T28906 | T6603185 | T-6603185,T 6603185 | |
T6603185 is a novel inhibitor of peroxiredoxin (Prx) and thioredoxin (Trx) systems. | |||
T70131 | TPP2a bromide | ||
TPP2a is a mitochondrial thioredoxin reductase (TrxR) inhibitor. | |||
T11130 | DVD-445 | Others | |
Dvd-445 has good anti-cancer effect.Dvd-445 is an effective peptide covalent thioredoxin reductase 1 (TrxR1) inhibitor with IC50 value of 0.60 mol/L M. | |||
T34922 | TRFS-red | TRFSred | |
TRFS-red is the first red emission off-on probe for thioredoxin reductase. | |||
T33413 | Mito-TRFS | MitoTRFS | |
Mito-TRFS is the first off-on probe for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells. | |||
T40946 | Seph-PAO | ||
Seph-PAO, a modified form of polyalphaolefin (PAO) compound, is created by coupling a sepharose fluorophore. Its primary application lies in the detection of thioredoxin reductase (TrxR). |