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Cat No. | Product Name | Synonyms | Targets |
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T12990 | sPLA2-X Inhibitor 31 | Others | |
sPLA2-X Inhibitor 31 is a selective inhibitor of secreted phospholipase A2 type X (sPLA2-X) (IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively). | |||
T27731 | sPLA2 inhibitor 1 | KH-064,KH 064,KH064,5-BPP acid | |
KH064 is a sPLA2-IIA inhibitor of oral activity. | |||
T81115 | sPLA2-IIA Inhibitor | ||
The sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK, specifically cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2), which interacts with human IIA phospholipase A2 (hGIIA) to impede its ester bond hydrolyzing function. A... | |||
T2044 | Varespladib | LY315920 | Phospholipase |
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv... | |||
T39173 | Varespladib sodium | LY315920 sodium | |
Varespladib sodium (LY315920 sodium) is a highly potent and selective inhibitor of group IIA secretory phospholipase A2 (sPLA2), with an IC50 of 9 nM. It demonstrates significant inhibitory activity against sPLA2 in seru... | |||
T22950 | LY-311727 | LY 311727 | Others |
secreted phospholipase A2 (sPLA2) inhibitor | |||
T23547 | YM 26734 | Others | |
Competitive inhibitor of secretory phospholipase A2 (sPLA2) | |||
T25787 | Me-Indoxam | Methyl indoxam,Methyl-indoxam | |
Me-Indoxam is an inhibitor of sPLA2. It has no effect on arachidonic acid release and platelet activating factor synthesis. | |||
T61168 | CAY10590 | ||
CAY10590 (GK115) is a compound that functions as an inhibitor of secreted phospholipase A2 (sPLA2). It is commonly employed in research related to chronic inflammatory kidney diseases [1]. | |||
T37580 | Arachidonoyl thio-PC | ||
Arachidonoyl Thio-PC is a substrate for many phospholipase A2s (PLA2s) including sPLA2, cPLA2, and iPLA2. Cleavage of the sn-2 fatty acid by PLA2 results in generation of a free thiol which reacts with chromogenic reagen... | |||
T30831 | Cgp 43182 | Cgp-43182,Cgp43182 | |
CGP 43182 is an effective inhibitor of group IIA secretory phospholipase A2 (Group IIA sPLA2) activity in vitro, which can be used to prevent the synergistic effect of pro-inflammatory genes stimulated by cytokines media... | |||
T37221 | GK187 | ||
GK187 is an inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2), an enzyme involved in basal cell metabolism. It inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction in a mixed micelle activity assa... | |||
T75589 | Bitis Cornuta Venom | ||
Bitis Cornuta (Many-horned Adder) Venom, sourced from Bitis Cornuta, comprises snake venom phospholipase A2 (sPLA2) toxins that exhibit anticoagulant properties by inhibiting the prothrombinase complex, consequently prom... | |||
T37244 | Palmitoyl thio-PC | ||
Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrat... | |||
T37123 | 1,2-Dioctanoyl PC | ||
Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fat... | |||
T37785 | 1-Palmitoyl-2-linoleoyl PE | ||
Phosphatidylethanolamines are important components of cell membranes and biochemical pathways of fatty acid synthesis. 1-Palmitoyl-2-linoleoyl PE (PLPE) is one of the many phosphatidylethanolamines that may be present in... | |||
T35622 | FKGK 18 | ||
FKGK 18 is an inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). It inhibits GVIA iPLA2 by 99.9% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA... | |||
T10168 | 5-HT1A modulator 1 | 5-HT1Amodulator1 | Phospholipase , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM). | |||
T22589 | Asenapine hydrochloride | Others | |
Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. |
Cat No. | Product Name | Synonyms | Targets |
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T13206 | Tris(2,4-di-tert-butylphenyl)phosphate | Phospholipase | |
Tris(2,4-di-tert-butylphenyl)phosphate is a natural compound isolated from Vitex negundo L. with anti-inflammatory activity. | |||
T2907 | Tanshinone I | Tanshinone A | Phospholipase |
Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells. |
Cat No. | Product Name | Species | Expression System |
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TMPY-04016 | PLA2G2D Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
PLA2G2D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.5 kDa and the accession number is Q9UNK4. | |||
TMPY-04912 | PLA2G2A Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
PLA2G2A Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 15.3 kDa and the accession number is P31482. | |||
TMPY-01705 | PLA2G2A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PLA2G2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is A0A024RA96. | |||
TMPY-02181 | PLA2G12B Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein that belongs to the ... | |||
TMPY-02162 | Phospholipase A2 IIE/PLA2G2E Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Group IIE secretory phospholipase A2, also known as GIIE sPLA2, sPLA2-IIE, Phosphatidylcholine 2-acylhydrolase 2E and PLA2G2E is a secreted protein that belongs to the phospholipase A2 family. Mammalian secretory phospho... |