Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 5 days | $ 38.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 52.00 |
Description | Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. |
Targets&IC50 | 5-HT2A receptor:0.06 nM (Ki), 5-HT2C receptor:0.03 nM (Ki), 5-HT7 receptor:0.13 nM (Ki), D4 receptor:1.1 nM (Ki), D3 receptor:0.42 nM (Ki), SPLA2:2.5 nM (Ki), D2 receptor:1.3 nM (Ki) |
In vitro | Asenapine displays high affinity (pKi) for numerous receptors, including the serotonin 5-HT1A (8.6), 5-HT1B (8.4), 5-HT2A (10.2), 5-HT2B (9.8), 5-HT2C (10.5), 5-HT5A (8.8), 5-HT6 (9.5), and 5-HT7 (9.9) receptors, the adrenergic α1 (8.9), α2A (8.9), α2B (9.5), and α2C (8.9) receptors, the dopamine D1 (8.9), D2 (8.9), D3 (9.4), and D4 (9.0) receptors, and the histamine H1 (9.0) and H2 (8.2) receptors. Asenapine behaves as an antagonist at all receptors. |
Molecular Weight | 322.23 |
Formula | C17H17Cl2NO |
CAS No. | 1412458-61-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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Asenapine hydrochloride 1412458-61-7 Others Asenapine Hydrochloride inhibitor inhibit