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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2252 | UNC 669 | UNC669 | Epigenetic Reader Domain |
UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3. | |||
T5654 | Musk ketone | Others | |
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant. | |||
T67920 | HPPE | ||
HPPE is a selective inhibitor of Bach1 that acts non-electrophilically. HPPE targets the heme-binding sites on the Bach1 protein and leads to the alleviation of Bach1-mediated repression. | |||
T60066 | Thermospermine | N'-[3-(3-aminopropylamino)propyl]butane-1,4-diamine,1,12-Diamino-4,8-diazadodecane | Others |
Thermospermine is a structural isomer of spermine and plays a role in the repression of xylem differentiation. Thermospermine can be used in studies about acting as a plant growth regulator and serving in the control of ... | |||
T3685 | SR9009 | Stenabolic,REV-ERB Agonist II | Autophagy |
SR9009 (Stenabolic), a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBα/ERBβ (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during... | |||
T2548 | Diflorasone | Glucocorticoid Receptor | |
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti... | |||
T10605 | BRD-K98645985 | Others | |
BRD-K98645985 is a BAF transcriptional repression inhibitor (EC50: ~2.37 µM). It binds ARID1A-specific BAF complexes, potently reverses HIV-1 latency and prevents nucleosomal positioning. | |||
T69692 | BRD-K25923209 | ||
BRD-K25923209 is a novel inhibitor of BAF transcriptional repression. | |||
T26110 | Robotnikinin | ||
Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2. | |||
T69663 | G108 | ||
G108 is a Novel h-cGAS specific inhibitor for repression of dsDNA-triggered interferon expression (IC50 of 27.5 nM and 5150 nM for h-cGAS and m-cGAS, respectively). | |||
T81004 | Tetraproline | ||
Tetraproline, a sequence fragment of tristetraprolin (TTP), facilitates the repression and degradation of mRNAs containing AU-rich elements by recruiting the 4EHP-GYF2 cap-binding complex to TTP's tetraproline motifs [1]... | |||
T63551 | Glucocorticoid receptor-IN-1 | ||
Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50:... |