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Search Results for " repression "

12

Compounds

Cat No. Product Name Synonyms Targets
T2252 UNC 669 UNC669 Epigenetic Reader Domain
UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
T5654 Musk ketone Others
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
T67920 HPPE
HPPE is a selective inhibitor of Bach1 that acts non-electrophilically. HPPE targets the heme-binding sites on the Bach1 protein and leads to the alleviation of Bach1-mediated repression.
T60066 Thermospermine N'-[3-(3-aminopropylamino)propyl]butane-1,4-diamine,1,12-Diamino-4,8-diazadodecane Others
Thermospermine is a structural isomer of spermine and plays a role in the repression of xylem differentiation. Thermospermine can be used in studies about acting as a plant growth regulator and serving in the control of ...
T3685 SR9009 Stenabolic,REV-ERB Agonist II Autophagy
SR9009 (Stenabolic), a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBα/ERBβ (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during...
T2548 Diflorasone Glucocorticoid Receptor
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...
T10605 BRD-K98645985 Others
BRD-K98645985 is a BAF transcriptional repression inhibitor (EC50: ~2.37 µM). It binds ARID1A-specific BAF complexes, potently reverses HIV-1 latency and prevents nucleosomal positioning.
T69692 BRD-K25923209
BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.
T26110 Robotnikinin
Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2.
T69663 G108
G108 is a Novel h-cGAS specific inhibitor for repression of dsDNA-triggered interferon expression (IC50 of 27.5 nM and 5150 nM for h-cGAS and m-cGAS, respectively).
T81004 Tetraproline
Tetraproline, a sequence fragment of tristetraprolin (TTP), facilitates the repression and degradation of mRNAs containing AU-rich elements by recruiting the 4EHP-GYF2 cap-binding complex to TTP's tetraproline motifs [1]...
T63551 Glucocorticoid receptor-IN-1
Glucocorticoid receptor-IN-1 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. glucocorticoid receptor-IN-1 has good transcriptional repression, acting on hMMP1 ( IC50:...
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