prostaglandin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5014	Prostaglandin E2	PGE2,Dinoprostone,Prostaglandin E2 (PGE2)	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in a variety of physiological processes in the body, including smooth muscle contraction and relaxation, regulation of vasodilatation and constriction, re...		Endogenous Metabolite , Prostaglandin Receptor
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T36544	Prostaglandin D1	Prostaglandin D1
	Prostaglandin D1 is a prostaglandin that has contraction and relaxation effects on isolated human arteries and can inhibit ADP-induced platelet aggregation (IC50=320 ng/ml). Prostaglandin D1 can be used in metabolic stud...
T37328	Prostaglandin H1	Prostaglandin H1
	Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins. Prostaglandin H1 can be used in the study of inflammation.
T37919	Prostaglandin F1α	PGF1α,Prostaglandin F1α
	Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with...
T35992	Ent-Prostaglandin F2α	ent-Prostaglandin F2α
	ent-Prostaglandin F2α is the enantiomer of PGF2α and is found in urine.
T38195	Prostaglandin F2α Ethanolamide	Prostaglandin F2α Ethanolamide
	Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directl...
T36455	11β-Prostaglandin F2α	11β-Prostaglandin F2α
	11β-Prostaglandin F2α is a bioactive metabolite catalyzed by AKR1C3 that stimulates prostaglandin F receptors and induces slug expression in breast cancer. 11β-Prostaglandin F2α is also an endogenous metabolite present i...
T35991	Ent-Prostaglandin E2	ent-Prostaglandin E2
	Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of P...
T36238	6α-Prostaglandin I1	6α-Prostaglandin I1
	6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration depende...
T36239	6β-Prostaglandin I1	6β-Prostaglandin I1
	6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for aden...
T36144	11β-Prostaglandin E2	11β-PGE2,11β-Prostaglandin E2
	11β-PGE2 is the C-11 epimer of PGE2. It is a moderate inhibitor of PGE2 binding to rat hypothalamic membranes with a Ki value of 53 nM.[1] 11β-PGE2 also stimulates bone resorption in rats at concentrations of 10-8 to 10-...
T38389	Prostaglandin D2 Ethanolamide	Prostaglandin D2 Ethanolamide
	Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The ...
T27066	Prostaglandin G/H synthase 1 inhibitor	CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide	Others
	Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.		Others
T36158	8-iso Prostaglandin A2	8-iso Prostaglandin A2
	8-iso Prostaglandin A2 is an isoprostane produced by the nonenzymatic oxidation of arachidonic acid.
T36159	8-iso Prostaglandin E1	8-iso Prostaglandin E1
	8-iso Prostaglandin E1 causes spasm in the pulmonary veins of dogs and also acts as a vasodilator.
T36209	15-keto Prostaglandin A1	15-keto Prostaglandin A1
	Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 ...
T36041	16,16-dimethyl Prostaglandin A2	16,16-dimethyl Prostaglandin A2
	16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4...
T36213	16,16-dimethyl Prostaglandin D2	16,16-dimethyl Prostaglandin D2
	16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. It enhances ADP-induced human platelet aggregation and increases systemic blood pressure in rats.
T36726	6-keto Prostaglandin E1	6-keto Prostaglandin E1
	6-keto Prostaglandin E1 is a bioactive derivative of PGE1 that plays a role in antiplatelet aggregation and depolymerization.