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11β-Prostaglandin E2

Catalog No. T36144 CAS 38310-90-6

Synonyms: 11β-PGE2, 11β-Prostaglandin E2

11β-PGE2 is the C-11 epimer of PGE2. It is a moderate inhibitor of PGE2 binding to rat hypothalamic membranes with a Ki value of 53 nM.[1] 11β-PGE2 also stimulates bone resorption in rats at concentrations of 10-8 to 10-6 M which is similar to PGE2.2 11β-PGE2 inhibits PGE2 binding to the prostaglandin transporter protein with a Ki of 56 nM.[3]

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11β-Prostaglandin E2, CAS 38310-90-6

Pack Size	Availability	Price/USD
500 μg	35 days	$ 85.00
1 mg	35 days	$ 160.00
5 mg	35 days	$ 660.00
10 mg	35 days	$ 1,140.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	11β-PGE2, 11β-Prostaglandin E2
Molecular Weight	352.47
Formula	C20H32O5
CAS No.	38310-90-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMF: >100 mg/mL (from PGE2)

DMSO: >100 mg/mL (from PGE2)

Ethanol: >100 mg/mL (from PGE2)

References and Literature

1. Dray, F., and Heaulme, M. Prostaglandins of the E series inhibit release of noradrenaline in rat hypothalamus by a mechanism unrelated to classical α2 adrenergic presynaptic inhibition. Neuropharmacology 23, 457-462 (1984). 2. Raisz, L.G., and Woodiel, F.N. Effect of alterations in the cyclopentane ring on bone resorptive activity of prostaglandin. Prostaglandins 37, 229-235 (1989). 3. Itoh, S., Lu, R., Bao, Y., et al. Structural determinants of substrates for the prostaglandin transporter PGT. Molecular Pharmacology 50, 736-742 (1996).

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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