Powder: -20°C for 3 years | In solvent: -80°C for 1 year
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by <90% at a concentration of 4 μg/ml. Daily infusion of 10 μg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 230.00 | |
5 mg | 35 days | $ 987.00 | |
10 mg | 35 days | $ 1,790.00 |
Description | 16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 μg/ml. Daily infusion of 10 μg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time. |
Synonyms | 16,16-dimethyl Prostaglandin A2 |
Molecular Weight | 362.5 |
Formula | C22H34O4 |
CAS No. | 41691-92-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: >50 mg/mL (from PGA1)
Ethanol: >100 mg/mL (from PGA1)
DMF: >75 mg/mL (from PGA1)
PBS (pH 7.2): >2.4 mg/mL (from PGA1)
You can also refer to dose conversion for different animals. More
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16,16-dimethyl Prostaglandin A2 41691-92-3 16,16dimethyl Prostaglandin A2 16,16-dimethyl Prostaglandin A-2 16,16 dimethyl Prostaglandin A2 inhibitor inhibit