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Prostaglandin F2α Ethanolamide

Catalog No. T38195 CAS 353787-70-9

Synonyms: Prostaglandin F2α Ethanolamide

Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs. PGF2α-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents.

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Prostaglandin F2α Ethanolamide Chemical Structure

Prostaglandin F2α Ethanolamide, CAS 353787-70-9

Pack Size	Availability	Price/USD
1 mg	Inquiry	$ 578.00
5 mg	Inquiry	$ 1,428.00
10 mg	Inquiry	$ 2,158.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Prostaglandin F2α Ethanolamide
Molecular Weight	397.55
Formula	C22H39NO5
CAS No.	353787-70-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL

PBS (pH 7.2): 10 mg/mL

DMF: Miscible

Ethanol: Miscible

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Prostaglandin F2α Ethanolamide 353787-70-9 Prostaglandin F2a Ethanolamide Prostaglandin F2alpha Ethanolamide Prostaglandin F-2α Ethanolamide inhibitor inhibit

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