11
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1939 | DMOG | Dimethyloxalylglycine,Dimethyloxallyl Glycine,Dimethyloxaloylglycine | HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy |
DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase. | |||
T12644L | (S)-Thalidomide | (S)-(-)-Thalidomide | Apoptosis |
(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic and pro-apoptotic activities, and is used in the study of leprosy erythema nodosu... | |||
T3843 | Pinosylvin | 3,5-stilbenediol,5-Styrylresorcinol | Apoptosis , Others , Antibacterial , Autophagy |
Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor. | |||
T36715 | Tetrac | Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid | Apoptosis , EGFR |
Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac... | |||
T1185 | Rofecoxib | MK 966,MK-0966 | COX |
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of pheny... | |||
T69599 | ABT-510 | ||
ABT-510 is synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascul... | |||
T11325 | Frondoside A | Others | |
possesses anticancer, anti-invasive, anti-metastasis, anti-angiogenic and pro-apoptosis properties with high safety.Frondoside A, a natural glycoside extracted from the sea cucumber, Cucumaria frondosa, | |||
T82633 | Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2 | ||
Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2 is a linear peptide derived from the laminin B1 chain, which disrupts tumor cell adherence and invasion into the basement membrane and exhibits anti-angiogenic properties [1]. | |||
T28874 | SU11652 | SU-11652,SU 11652 | |
SU11652 is a potent cell-permeable pyrrole-indolinone compound. SU11652 acts as an ATP-competitive tyrosine kinase receptor and angiogenic inhibitor with greater selectivity for PDGFR-β (PDGFRβ, IC50 = 3 nM), Flk-1 (VEGF... | |||
T69555 | XUN49524 | ||
XUN49524 also known as Vezf1-IN-T4, is an inhibitor of the pro-angiogenic activity of the zinc finger transcription factor Vezf1. XUN49524 was first reported in Molecules (2018), 23(7), 1615/1-1615/15 . This product has ... | |||
T69223 | CC-1088 | ||
CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). SelCIDs inhibit phosphodiesterase-4 (PDE 4),... |